Top Secret Nutrition Cleanse & Detox is a comprehensive 4-part, 7-day whole-body cleanse formula — 42 vegetarian capsules covering internal cleansing, gastrointestinal support, liver detoxification, and prebiotic/probiotic gut restoration in a single integrated protocol. The formula is built around a botanically dense ingredient list: Psyllium Seed and Senna for gentle elimination support, Indole-3-Carbinol (I3C from cruciferous vegetables) and D-Glucarate for toxin binding and elimination, Aloe Vera Extract for GI soothing and bowel support, Milk Thistle Extract and Turmeric Extract for liver protection and detoxification, and a Prebiotic/Probiotic Blend for gut flora restoration following the cleanse. 42 veggie caps — 7-day supply at 6 capsules daily (3 capsules twice daily, morning and before bed). Manufactured in the USA. Take with 8oz water. Drink 10 or more glasses of water per day during the 7-day protocol. Not for use by persons under 18. Not for pregnant or nursing women. Consult a physician before use if taking any prescription medications.†
Supplement Facts — Top Secret Nutrition Cleanse & Detox (Per 3 Capsules / 2x Daily / 42 Veggie Caps)
Part 1 — Internal Cleansing Blend
Psyllium Seed — soluble fiber for gentle colon sweep and toxin binding
Senna — gentle stimulant laxative for elimination support and bowel regularity
Indole-3-Carbinol (I3C) — cruciferous vegetable compound supporting Phase II liver detoxification and estrogen metabolism
D-Glucarate (Calcium D-Glucarate) — supports glucuronidation, a key liver detoxification pathway for toxin excretion
Part 2 — Gastrointestinal Blend
Aloe Vera Extract — soothing GI support, reduces bloating, supports intestinal transit
Part 3 — Liver Cleansing Blend
Milk Thistle Extract (Silymarin) — hepatoprotective, supports liver cell regeneration and detoxification
Turmeric Extract (Curcumin) — antioxidant and anti-inflammatory liver and bile support
Part 4 — Prebiotic/Probiotic Blend
Prebiotic/Probiotic Blend — restores essential gut bacteria balance and microbiome health following the cleanse
Other Ingredients: Vegetable Cellulose (capsule), Magnesium Stearate, Microcrystalline Cellulose, Silicon Dioxide
Vegetarian capsule. Manufactured in the USA.
Individual blend doses are not disclosed — proprietary blend format
42 veggie caps — 7-day supply at 6 capsules daily
Take 3 capsules twice daily — morning and before bed
Always take with 8oz of water
Drink 10 or more glasses of water per day throughout the 7-day protocol
Do not exceed 6 capsules per day
Not for use by persons under 18. Not for pregnant or nursing women.
Consult a physician before use if taking any prescription medications or having any medical condition
The Four-Part System — Why Each Layer Is Here
Most cleanse products address one dimension of the detoxification process — a fiber supplement for colon cleansing, a milk thistle capsule for liver support, or a probiotic for gut flora. Top Secret Nutrition Cleanse & Detox is designed as an integrated protocol where all four dimensions are addressed simultaneously in a single 7-day formula. The logic is mechanistically sound: effective whole-body detoxification requires the elimination channels (colon, via fiber and gentle laxative support), the primary detox organ (liver, via Milk Thistle and Turmeric), the specific biochemical detox pathways (Phase II liver detoxification via I3C and D-Glucarate), and the gut flora restoration that a cleanse protocol can disrupt (via the prebiotic/probiotic blend). Running all four simultaneously produces a more complete cleanse result than any single-mechanism product.†
The Key Botanicals — What Each One Does
Psyllium Seed — Soluble Fiber and Colon Sweep
Psyllium husk and seed is one of the most well-documented soluble fiber sources in nutritional science — it is the primary active ingredient in FDA-approved fiber supplements like Metamucil. In the colon, psyllium absorbs water and forms a gel that bulks stool, stimulates peristalsis (the muscular contractions that move waste through the colon), and serves as a physical sweep that carries accumulated waste, undigested material, and bound toxins through and out of the large intestine. As a soluble fiber, psyllium also functions as a prebiotic — fermented by beneficial colonic bacteria to produce short-chain fatty acids that support colonocyte (colon cell) health. The inclusion of psyllium in the Internal Cleansing Blend provides the physical fiber-based elimination support that the other detox mechanisms depend on — toxins released from the liver through bile flow need to be captured and excreted through the colon rather than reabsorbed.†
Senna — Gentle Elimination Support
Senna (Cassia senna) is an FDA-approved over-the-counter stimulant laxative — the active compounds are sennosides, which stimulate the muscles of the colon wall to increase peristaltic contractions and accelerate bowel transit time. Senna is one of the most commonly used and well-studied natural laxatives, with a long history of use in traditional medicine systems including Ayurveda and Traditional Chinese Medicine. In the context of a 7-day cleanse protocol, Senna's stimulant laxative effect complements psyllium's bulk-forming mechanism — psyllium adds volume and captures toxins, while Senna ensures those contents are moved through efficiently. Maximum continuous use of Senna is generally recommended at 1-2 weeks — the 7-day duration of this cleanse protocol aligns appropriately with this recommendation.†
Indole-3-Carbinol (I3C) — Phase II Liver Detoxification
Indole-3-Carbinol is a naturally occurring compound found in cruciferous vegetables (broccoli, cabbage, Brussels sprouts, kale) — it forms from glucosinolates when these vegetables are chewed or processed. I3C and its primary metabolite DIM (Diindolylmethane) are among the most extensively researched botanical compounds for their effects on Phase II liver detoxification — specifically the cytochrome P450 enzyme induction and glucuronidation pathways that the liver uses to convert fat-soluble toxins into water-soluble, excretable metabolites. I3C has documented effects on estrogen metabolism (promoting the 2-hydroxylation pathway over the 16-hydroxylation pathway) and is one of the reasons cruciferous vegetables are specifically associated with cancer risk reduction in epidemiological research.†
D-Glucarate — Glucuronidation Support
Calcium D-Glucarate is the calcium salt of D-glucaric acid — a compound found naturally in fruits and vegetables that inhibits beta-glucuronidase, an enzyme produced by certain gut bacteria. Beta-glucuronidase cleaves the glucuronide bond that the liver uses to tag toxins and hormones for excretion — when beta-glucuronidase is overactive, it breaks this bond and releases toxins back into circulation rather than allowing them to be excreted. By inhibiting beta-glucuronidase, D-Glucarate supports the liver's glucuronidation detoxification pathway and promotes the complete excretion of tagged toxins and hormones rather than their recycling. D-Glucarate specifically supports the detoxification of environmental toxins, excess estrogens, and pharmaceutical metabolites through this mechanism.†
Milk Thistle Extract (Silymarin) — The Hepatoprotective Anchor
Milk Thistle extract standardized for Silymarin is the most extensively researched hepatoprotective botanical in Western medicine — with clinical evidence across liver disease contexts including alcoholic liver disease, non-alcoholic fatty liver disease, drug-induced hepatotoxicity, and viral hepatitis. Silymarin's mechanisms include antioxidant protection of hepatocytes from free radical damage, inhibition of toxin entry into liver cells (blocking the transporters toxins use), stimulation of protein synthesis for liver cell regeneration, and anti-inflammatory activity reducing hepatic inflammation. Including Milk Thistle in the liver cleansing blend while simultaneously mobilizing toxins through the Internal Cleansing Blend is mechanistically appropriate — hepatoprotection is particularly relevant when toxins are being mobilized and processed.†
Turmeric Extract (Curcumin) — Antioxidant and Bile Support
Turmeric Extract (Curcumin) adds antioxidant and anti-inflammatory support to the liver cleansing blend alongside Milk Thistle. Curcumin's hepatoprotective effects include reduction of oxidative stress in liver tissue, inhibition of NF-κB inflammatory signaling in hepatocytes, and promotion of bile production and flow (choleretic effect) — increased bile flow supports both fat-soluble toxin excretion through the biliary system and fat digestion. Curcumin and Silymarin work through complementary rather than redundant mechanisms, providing broader hepatoprotective coverage together than either alone.†
Aloe Vera Extract — GI Soothing and Transit Support
Aloe Vera's inner leaf gel contains acemannan (a polysaccharide with prebiotic and anti-inflammatory properties), anthraquinone glycosides (which have mild laxative effects), and compounds that soothe and protect the intestinal mucosa. In a cleanse protocol, Aloe Vera's GI support covers the intestinal health dimension — reducing the irritation and inflammation that cleanse protocols involving Senna and fiber can sometimes produce, while also supporting the bowel transit that moves the cleanse results through the GI system. Reviews of this product specifically note that it produces a "gentle cleanse" with no stomach pain — consistent with Aloe Vera's soothing anti-inflammatory presence alongside the more active elimination compounds.†
The Prebiotic/Probiotic Blend — Restoring Balance After the Cleanse
A frequently overlooked problem with cleanse products that use stimulant laxatives and fiber sweeps is the disruption they can cause to the established gut flora — the beneficial bacteria that maintain the gut's immune function, metabolic activity, and overall microbiome health. By including a Prebiotic/Probiotic Blend in the same formula, Top Secret Nutrition Cleanse & Detox addresses this problem in the same 7-day protocol that causes it. The probiotics introduce beneficial bacterial strains to replace any that are flushed out during the cleanse process. The prebiotics (fermentable fibers that beneficial bacteria use as fuel) support the growth and establishment of these bacterial populations. The result is a cleanse that leaves the gut microbiome restored rather than depleted.†
The 7-Day Protocol — How It Works
Top Secret Nutrition Cleanse & Detox is designed as a structured 7-day protocol rather than an ongoing daily supplement. The 42 capsules provide exactly 7 days of use at the recommended 6 capsules daily (3 in the morning, 3 before bed) — the fixed supply creates a defined start and end, which is clinically appropriate for Senna-containing formulas where continuous use beyond 1-2 weeks can reduce efficacy and cause dependency. The twice-daily dosing (morning and before bed on an empty or light stomach) ensures continuous coverage of the four formula systems throughout the day and night. Drinking 10 or more glasses of water throughout the 7 days is essential — the fiber and detox mechanisms require adequate hydration to function properly, and inadequate water intake during a psyllium-based cleanse can produce constipation rather than the intended effect.†
Frequently Asked Questions
Why is drinking 10 glasses of water per day required?
Psyllium seed is the primary fiber compound in the Internal Cleansing Blend — it absorbs water in the colon to form the gel matrix that produces its beneficial effects. Without adequate water, psyllium can swell in the esophagus or intestines and produce a blockage rather than the intended cleansing effect. Adequate hydration also supports kidney filtration of the water-soluble toxin metabolites that the liver processes during the cleanse, and helps prevent the dehydration that stimulant laxatives like Senna can cause through increased bowel water loss.†Can Top Secret Nutrition Cleanse & Detox be repeated after the 7 days?
Extended continuous use of Senna is not recommended beyond 1-2 weeks. After completing the 7-day protocol, a break of at least 2-4 weeks is advisable before repeating the cleanse. This allows the natural bowel motility to reassert itself without laxative dependence and allows gut flora to stabilize. Consult a physician before repeating if you have any GI conditions.†What are Indole-3-Carbinol and D-Glucarate and why are they in a cleanse formula?
Indole-3-Carbinol (from cruciferous vegetables) and D-Glucarate both support Phase II liver detoxification — the biochemical processes the liver uses to tag fat-soluble toxins for excretion. I3C upregulates the enzymes that convert toxins into excretable forms. D-Glucarate inhibits the enzyme that would recycle tagged toxins back into circulation rather than excreting them. Both compounds address the liver's biochemical detoxification efficiency rather than its general health — they work alongside Milk Thistle and Turmeric's hepatoprotective mechanisms to produce more complete liver detox support.†Is Top Secret Nutrition Cleanse & Detox appropriate for individuals with IBS or other GI conditions?
Individuals with Irritable Bowel Syndrome, Crohn's disease, ulcerative colitis, or any other diagnosed GI condition must consult a physician before use. Senna is specifically contraindicated in inflammatory bowel conditions, and the fiber sweep from psyllium can exacerbate IBS symptoms in sensitive individuals. This product is designed for generally healthy adults without pre-existing GI conditions.†
How to Take Top Secret Nutrition Cleanse & Detox
Take 3 capsules in the morning and 3 capsules before bed. Always take each serving with 8oz of water. Drink 10 or more glasses of water throughout each day of the 7-day cleanse — adequate hydration is essential for the fiber and detox mechanisms to function safely and effectively. Do not exceed 6 capsules per day. The 42-capsule container provides exactly 7 days of use — complete the full protocol without interruption for best results. Do not use this product as a substitute for a varied diet or a healthy lifestyle. Not for use by persons under 18. Not for pregnant or nursing women. Consult a physician before use if taking any prescription or over-the-counter medications or having any medical condition. Individuals with gastrointestinal conditions (IBS, Crohn's, colitis) must not use without physician clearance — Senna is contraindicated in inflammatory bowel conditions.†
Why Buy at Get Yok'd
Real-time inventory across all five Southern California stores
Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
Authorized Top Secret Nutrition retailer — carrying Cleanse & Detox alongside the full Top Secret Nutrition lineup
Staff who can help you incorporate a 7-day cleanse protocol into your overall health and supplement routine
One of the best loyalty programs in the supplement industry — earn rewards on every purchase
Who Should Not Take Cleanse & Detox
Not for persons under 18 years of age
Not for pregnant or nursing women
Individuals with Irritable Bowel Syndrome, Crohn's disease, ulcerative colitis, or any inflammatory bowel condition must not use without physician clearance — Senna is contraindicated in these conditions
Individuals with intestinal obstruction or difficulty swallowing should not use psyllium-containing products without physician clearance
Individuals taking blood thinners should consult a physician — Turmeric has mild anticoagulant properties
Individuals taking hormonal medications (birth control, HRT) should consult a physician — I3C and D-Glucarate affect estrogen metabolism and may interact with hormonal medications
Individuals taking any prescription medications should consult a physician before use — this formula contains compounds that affect hepatic cytochrome P450 enzymes and may alter medication metabolism
Do not exceed the recommended dose or use beyond the 7-day protocol without physician guidance
Do not use if safety seal is broken or missing
Keep out of reach of children.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.