Inspired Nutraceuticals - GLX - 120 Capsules

Inspired Nutraceuticals GLX is a 4-in-1 oral GLP-1 metabolic support system — a stimulant-free formula that activates the body's natural GLP-1 production pathway, improves glucose disposal and insulin sensitivity, supports satiety through a clinically studied peptide complex, and rebuilds the gut-brain-metabolism axis through three targeted probiotic strains. Per 4-capsule serving: 500mg DNF-10 (hydrolyzed yeast satiety peptide), 250mg InnoSlim® (AMPK activation and glucose partitioning), 200mg GlucoVantage® (Dihydroberberine, 5x more bioavailable than standard Berberine), Banaba Leaf Extract (Corosolic Acid), Cinnamon Extract, Chromax® (Chromium Picolinate), and the PRO-GLX TriBiomic Complex — Bifidobacterium lactis B420, Clostridium butyricum, and Akkermansia muciniphila. Zero stimulants. Zero synthetic hormones. No GLP-1 receptor agonism. GLX activates your own endogenous GLP-1 release rather than replacing it with an exogenous pharmaceutical compound. 120 capsules per container — 30 servings. Take 4 capsules 20-30 minutes before your first meal on an empty stomach. Recommended for 90+ days of consistent use. Consult a physician before use if taking any medications for diabetes, hypertension, or thyroid conditions. California Prop 65 Warning applies.†

Supplement Facts — Inspired Nutraceuticals GLX (Per 4 Capsules / 30 Servings)

GLP-1 Activator and Satiety Peptide

• DNF-10 (Hydrolyzed Yeast Peptide Complex) — 500mg

Glucose Disposal and Insulin Sensitization

• InnoSlim® (Panax notoginseng Root + Astragalus membranaceus Root) — 250mg
• GlucoVantage® (Dihydroberberine / DHB) — 200mg
• Banaba Leaf Extract (standardized for Corosolic Acid)
• Cinnamon Extract
• Chromax® (Chromium Picolinate) — Chromium

PRO-GLX TriBiomic Complex (GLP-1 Specific Probiotics)

• Bifidobacterium lactis B420 — glucose tolerance and body fat support
• Clostridium butyricum — GLP-1 expression enhancement via butyrate
• Akkermansia muciniphila — gut permeability reduction and metabolic signaling

• Zero stimulants. Zero caffeine. Zero synthetic hormones.
• 120 capsules per container — 30 servings at 4 capsules per day
• Take 4 capsules 20-30 minutes before your first meal on an empty stomach
• Follow immediately with a well-balanced meal — do not take without eating shortly afterward
• Recommended consistent use: 90+ days for full synergistic effect
• Not a GLP-1 receptor agonist — activates the body's natural GLP-1 production pathway
• Consult a physician before use if taking medications for diabetes, hypertension, or thyroid conditions
• California Prop 65 Warning applies.

GLX and the GLP-1 Moment — What This Formula Is and What It Isn't

GLP-1 (Glucagon-Like Peptide-1) became one of the most discussed topics in medicine and popular culture when semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) demonstrated dramatic and consistent weight loss results through GLP-1 receptor agonism. Pharmaceutical GLP-1 receptor agonists work by directly binding GLP-1 receptors throughout the body at pharmacological doses — producing powerful appetite suppression, slowing of gastric emptying, and significant reduction in food intake. They require a prescription, are self-injected weekly, and carry a documented side effect profile including nausea, vomiting, constipation, gastroparesis, pancreatitis risk, and in some cases, muscle mass loss alongside the fat loss.†

GLX is not a GLP-1 receptor agonist and is not a pharmaceutical. It does not directly activate GLP-1 receptors at pharmacological levels. What it does is support the body's natural GLP-1 production through the gut-brain-metabolism axis — using clinically studied nutrients and probiotic strains that stimulate the L-cells in the intestinal lining to release more of the body's own GLP-1 in response to meals. This is the natural pathway through which GLP-1 works in the body without pharmacological intervention — and it is the pathway that gut health, dietary fiber, certain plant extracts, and specific probiotic strains have documented effects on. GLX's design is to optimize this natural pathway comprehensively, covering GLP-1 activation, glucose disposal, satiety, and the gut microbiome simultaneously.†

The Four Systems — What Each Layer Does

System 1: GLP-1 Activation — DNF-10 at 500mg

DNF-10 is a proprietary hydrolyzed yeast peptide complex developed by Ingredia — a French ingredient manufacturer with a significant clinical research investment behind this specific ingredient. DNF-10 is derived from the controlled enzymatic hydrolysis of Saccharomyces cerevisiae (baker's yeast), producing a complex of short peptides that interact with satiety receptors in the gut and central nervous system. The primary documented mechanism is GLP-1 stimulation: DNF-10 has been shown in human clinical trials to increase endogenous GLP-1 secretion, enhancing the gut's own hormonal signaling for satiety and appetite suppression.†

Multiple randomized, double-blind, placebo-controlled human trials have been conducted on DNF-10. A study published in Nutrients (2021) found that subjects receiving 500mg of DNF-10 daily for 12 weeks showed significantly greater reductions in food intake, body weight, and waist circumference compared to placebo — specifically through reduced caloric consumption driven by enhanced satiety signaling. The 500mg dose in GLX is the exact dose used in these positive clinical trials — Inspired Nutraceuticals uses the full research dose rather than a reduced amount for cost savings. The mechanism of action — increasing the body's own GLP-1 — is what positions DNF-10 as the central GLP-1 activating ingredient in the GLX formula.†

System 2: Glucose Disposal and AMPK Activation

InnoSlim® — 250mg: InnoSlim® is NuLiv Science's patented combination of Panax notoginseng root and Astragalus membranaceus root — the same NuLiv Science that produces Senactiv® (found in Axe & Sledge Intake). InnoSlim's primary mechanisms are AMPK activation and intestinal glucose transport modulation. AMPK (AMP-Activated Protein Kinase) is the master metabolic regulator that governs glucose uptake into muscle cells, fatty acid oxidation, and mitochondrial biogenesis — it is the same enzyme activated by Metformin (the most prescribed diabetes medication in the world). InnoSlim activates AMPK through plant saponin mechanisms, driving muscle cells to take up glucose from the bloodstream and burn it for energy rather than allowing it to be stored as fat. Simultaneously, InnoSlim reduces the expression of SGLT1 (Sodium-Glucose Linked Transporter 1) in the intestinal lining, decreasing the absorption rate of dietary glucose into systemic circulation. The combined effect is less glucose entering the blood from food (reduced intestinal absorption) and more glucose cleared from the blood into muscle (AMPK-driven muscle uptake). Published research on InnoSlim has documented reductions in blood glucose, improvements in adiponectin levels, and reductions in insulin resistance in human subjects.†

GlucoVantage® (Dihydroberberine / DHB) — 200mg: GlucoVantage® is NNB Nutrition's patented Dihydroberberine — the reduced, more bioavailable metabolite of Berberine. Standard Berberine is one of the most studied natural compounds for blood glucose management, with multiple meta-analyses showing effects comparable to Metformin in Type 2 diabetes management. However, standard Berberine has poor and variable oral bioavailability due to rapid intestinal metabolism and P-glycoprotein efflux. Dihydroberberine (DHB) bypasses this limitation — it is absorbed more efficiently in the intestine and converted back to Berberine in the body's tissues, achieving the same active Berberine concentration at approximately 1/5 the oral dose. GlucoVantage® is documented as 5x more bioavailable than standard Berberine, meaning 200mg of GlucoVantage® delivers equivalent active Berberine exposure to 1,000mg of standard Berberine. Berberine/DHB's mechanisms include AMPK activation (synergistic with InnoSlim), inhibition of intestinal glucose absorption, improved insulin receptor sensitivity, and reduction of hepatic glucose production (gluconeogenesis). DHB is one of the most compelling additions to a GLP-1 support formula because Berberine has independent documented effects on GLP-1 secretion — it activates L-cells in the intestine to increase GLP-1 release through AMPK-dependent pathways.†

Banaba Leaf Extract (Corosolic Acid): Banaba (Lagerstroemia speciosa) leaf extract standardized for Corosolic Acid is a traditional Southeast Asian plant with well-documented glucose disposal mechanisms. Corosolic Acid has been shown to activate glucose transport into cells independently of insulin, reduce intestinal glucose absorption, and inhibit pancreatic alpha-glucosidase (the enzyme that breaks dietary starch into glucose for absorption). Human clinical trials on Banaba extract have documented post-meal blood glucose reductions within 60 minutes — a rapid glycemic support effect that makes it particularly relevant when taken before the first meal as GLX is designed to be.†

Cinnamon Extract: Cinnamon (Cinnamomum verum / Ceylon Cinnamon) extract provides MHCP (Methylhydroxychalcone Polymer) — the active compound responsible for cinnamon's insulin-sensitizing effects. MHCP has been shown to activate insulin receptors on muscle and fat cells, improving the efficiency of insulin signaling and increasing glucose uptake at lower insulin levels. Cinnamon extract at meaningful doses also inhibits intestinal glucose absorption enzymes. Its inclusion alongside InnoSlim, GlucoVantage, and Banaba creates a four-mechanism glucose disposal stack covering AMPK activation, intestinal absorption reduction, insulin receptor sensitization, and post-meal glycemic response from multiple simultaneous mechanisms.†

Chromax® (Chromium Picolinate): Chromax® is Nutrition 21's patented Chromium Picolinate — the most clinically studied chromium form with documented superiority in bioavailability versus generic chromium supplements. Chromium is an essential trace mineral that potentiates insulin signaling — it interacts with the insulin receptor complex and enhances the receptor's response to insulin, improving glucose clearance from the blood. Chromax has clinical data on appetite reduction, carbohydrate craving suppression, and improved glycemic control. Chromium deficiency is common and contributes to insulin resistance and poor glycemic control — Chromax ensures chromium adequacy for optimal insulin efficiency throughout the formula's glucose disposal mechanisms.†

System 3: PRO-GLX TriBiomic Complex — The Gut-Brain-Metabolism Axis

The three-probiotic complex in GLX is what genuinely distinguishes it from conventional GDA or glucose disposal supplements — and it represents the most cutting-edge scientific framing in the formula. The gut microbiome's role in GLP-1 secretion, glucose metabolism, and body weight regulation has been one of the most active areas of metabolic research over the past decade. Specific bacterial strains have documented, reproducible effects on GLP-1 production and metabolic signaling that operate through entirely different mechanisms from the botanical and branded ingredient compounds above.†

Bifidobacterium lactis B420: B420 is a specific, patented strain of Bifidobacterium lactis with one of the most robust clinical evidence bases in the gut health and metabolic space. A 2019 double-blind, randomized controlled trial published in EBioMedicine documented that B420 supplementation significantly reduced body fat mass, waist circumference, and food intake in overweight subjects versus placebo over 6 months. The mechanism involves improved intestinal barrier integrity (reducing endotoxin translocation that drives inflammation and insulin resistance), improved glucose tolerance, and modulation of the gut microbiome composition toward a metabolically favorable profile.†

Clostridium butyricum: Clostridium butyricum is the primary intestinal producer of butyrate — the short-chain fatty acid that serves as the main energy substrate for colonocytes, maintains gut barrier function, and critically, stimulates GLP-1 secretion from intestinal L-cells through GPR41 and GPR43 (short-chain fatty acid receptors) activation. Research specifically on Clostridium butyricum has documented its ability to increase GLP-1 levels through butyrate-mediated L-cell stimulation — making it the most directly GLP-1-relevant probiotic in the TriBiomic complex. Elevated endogenous GLP-1 from gut bacterial butyrate production is one of the mechanisms through which dietary fiber and fermented foods improve metabolic health — Clostridium butyricum provides this mechanism in probiotic form.†

Akkermansia muciniphila: Akkermansia muciniphila has become one of the most researched gut bacteria in metabolic health over the past five years. Research consistently associates higher levels of Akkermansia with lower body fat, better glucose tolerance, reduced inflammation, and improved metabolic health — and lower Akkermansia abundance with obesity, Type 2 diabetes, and metabolic syndrome. Akkermansia's primary mechanism is mucus layer integrity maintenance: it colonizes and feeds on the intestinal mucus layer, producing short-chain fatty acids and signaling molecules that strengthen the gut barrier and reduce intestinal permeability. Reduced gut permeability means less endotoxin (LPS) translocation from the gut into systemic circulation — LPS-driven systemic inflammation is a major driver of insulin resistance, GLP-1 receptor downregulation, and metabolic dysfunction. Published research on Akkermansia muciniphila supplementation has documented improvements in insulin sensitivity, reduced waist circumference, and favorable metabolic marker changes in overweight and obese subjects.†

GLX vs. Prescription GLP-1 Medications — An Honest Comparison

Prescription GLP-1 receptor agonists (semaglutide, tirzepatide) are among the most effective pharmacological interventions for obesity ever studied — average weight loss of 15-20%+ of body weight in clinical trials at pharmacological doses, with documented cardiovascular risk reduction. They work by directly activating GLP-1 receptors at doses that produce supraphysiological receptor activation. GLX does not produce this level of effect — Inspired Nutraceuticals does not claim that it does, and this description does not suggest otherwise. GLX works by supporting the body's natural GLP-1 production, improving glucose handling, and rebuilding the gut microbiome environment that GLP-1 signaling depends on. The effect size is meaningfully smaller than pharmaceutical GLP-1 agonists and develops more gradually over weeks to months of consistent use.†

The relevant comparison is not "GLX vs. Ozempic" — it's "GLX vs. doing nothing" or "GLX vs. standard diet alone." In that context, the clinical evidence for DNF-10 (500mg), InnoSlim, GlucoVantage/DHB, and the probiotic strains collectively supports meaningful improvements in appetite control, glucose management, and metabolic health over a 90+ day period of consistent use. For individuals who are not candidates for or not interested in prescription GLP-1 medications, GLX represents a genuinely science-backed natural alternative — not a pharmaceutical replacement, but a comprehensive metabolic support system.†

Frequently Asked Questions

1. How quickly will I notice effects from GLX?
   The appetite and satiety effects from DNF-10 may begin within the first 1-2 weeks. The glucose disposal benefits from InnoSlim, GlucoVantage, and Chromax are measurable from the first dose in terms of post-meal glucose response, though the subjective experience (more stable energy after meals, reduced cravings) typically develops over 2-4 weeks. The probiotic strains require 4-8 weeks to establish meaningful colonization and microbiome remodeling. Full synergistic effect across all four systems is why Inspired Nutraceuticals recommends at least 90 days of consistent use — the gut microbiome component takes the longest to deliver its maximum contribution.†
2. Can GLX be used alongside prescription GLP-1 medications?
   Consult your physician before combining GLX with any prescription medications — particularly semaglutide, tirzepatide, or other GLP-1 receptor agonists, as well as any diabetes medications (Metformin, sulfonylureas, insulin). The glucose-lowering mechanisms in GLX (InnoSlim, GlucoVantage, Chromax, Banaba) may compound the blood glucose-lowering effects of prescription medications, potentially causing hypoglycemia. This is a physician conversation, not a self-assessment decision.†
3. Is GLX a stimulant-free formula?
   Yes — completely. GLX contains zero caffeine, zero stimulants, and no adrenergic compounds. The appetite suppression and metabolic support in GLX operate entirely through hormonal (GLP-1), enzymatic (AMPK, glucose transporters), and microbiome (probiotic) mechanisms. It can be taken at any time of day and has no effect on sleep.†
4. Why is the GlucoVantage® Dihydroberberine better than regular Berberine?
   Standard Berberine has poor and inconsistent oral bioavailability — it is rapidly metabolized in the intestine and subject to P-glycoprotein efflux, meaning a significant fraction of each dose is eliminated before reaching systemic circulation. Dihydroberberine (DHB) is the reduced form of Berberine that is more readily absorbed through intestinal epithelium, then converted back to Berberine in tissues. NNB Nutrition has documented GlucoVantage® as approximately 5x more bioavailable than standard Berberine — meaning 200mg of GlucoVantage delivers the active Berberine equivalent of approximately 1,000mg of standard Berberine. You get more active compound from a much smaller dose, in a much smaller capsule.†

How to Take Inspired Nutraceuticals GLX

Take 4 capsules 20-30 minutes before your first meal of the day, on an empty stomach. Do not take without eating shortly afterward — GLX's mechanisms are optimized in the context of a meal and some ingredients (particularly those affecting glucose absorption) are best active during food intake. Follow with a well-balanced meal. Do not exceed 4 capsules per day. Consistent daily use for 90+ days is recommended for full synergistic effect across all four systems. Zero stimulants — can be taken at any time of day appropriate to your first meal schedule. Consult a physician before use if taking any medications — particularly for diabetes, hypertension, or thyroid conditions, as GLX's glucose-lowering mechanisms may interact with these medications. Not for pregnant or nursing women. Not for individuals with gastroparesis or active pancreatitis. California Prop 65 Warning applies.†

Why Buy at Get Yok'd

• Real-time inventory across all five Southern California stores
• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
• Authorized Inspired Nutraceuticals retailer
• Staff who can walk you through GLX and help you understand how it fits into a comprehensive weight management or metabolic health stack
• One of the best loyalty programs in the supplement industry — earn rewards on every purchase

Who Should Exercise Caution with GLX

• Individuals taking diabetes medications (Metformin, insulin, sulfonylureas, GLP-1 receptor agonists, SGLT2 inhibitors) must consult a physician before use — GLX's glucose-lowering mechanisms may compound blood glucose reductions and cause hypoglycemia
• Individuals taking blood pressure medications should consult a physician — some ingredients may affect blood pressure
• Individuals with thyroid conditions should consult a physician before use
• Individuals with gastroparesis or active pancreatitis should not use without physician clearance — GLP-1 pathway activation slows gastric emptying, which may worsen gastroparesis
• Not for pregnant or nursing women
• Individuals with immune-compromised conditions should consult a physician before taking any probiotic supplement
• Consult a physician before use if taking any prescription medications
• California Prop 65 Warning applies.
• Keep out of reach of children.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.