Transparent Labs - Creatine HMB

Transparent Labs Creatine HMB combines the most research-validated performance supplement in sports nutrition with one of the most underutilized muscle-preservation compounds available — Beta-Hydroxy Beta-Methylbutyrate (HMB) — alongside Vitamin D3 and BioPerine for a complete, clinically dosed formula that goes beyond what standard creatine monohydrate products can offer. The International Society of Sports Nutrition (ISSN) has formally recognized creatine monohydrate as the most effective ergogenic nutritional supplement currently available. HMB is its evidence-based complement for muscle protein synthesis and anti-catabolism. No artificial sweeteners, colors, or flavors. Informed Choice certified. Third-party tested. 30 or 60 servings.†

Full Supplement Facts — Transparent Labs Creatine HMB (Per 1 Scoop Serving)

• Creatine Monohydrate — 5,000mg
• HMB (as myHMB Calcium Beta-Hydroxy Beta-Methylbutyrate Monohydrate) — 1,500mg
• Vitamin D3 (as Cholecalciferol) — 500 IU
• BioPerine (Black Pepper Extract, 95% Piperine) — 5mg
• No artificial sweeteners, colors, or flavors
• Informed Choice certified. Third-party tested for label accuracy and purity.
• Available in 30 or 60 servings. Available flavored and unflavored.

What's Inside Transparent Labs Creatine HMB

• Creatine Monohydrate — 5,000mg — 5g is the research-standard daily dose for creatine monohydrate, the form with the most extensive scientific validation of any supplement in existence. Creatine works by increasing phosphocreatine stores in skeletal muscle, which serve as the primary fuel reserve for ATP regeneration during high-intensity, short-duration efforts — the exact energy system that powers heavy lifting, sprinting, and explosive athletic movements. When phosphocreatine stores are depleted, performance drops precipitously. Consistent daily creatine supplementation keeps these stores saturated, allowing higher power output over more sets, faster recovery between sets, and accumulated improvements in lean muscle mass and strength that compound over weeks and months of training. The ISSN has concluded from its review of hundreds of peer-reviewed studies that creatine monohydrate is safe, effective, and the single most impactful ergogenic supplement available to athletes and active individuals.†
• myHMB (Calcium Beta-Hydroxy Beta-Methylbutyrate Monohydrate) — 1,500mg — myHMB is the patented, clinical-grade form of HMB with the highest purity specification and the form used in published efficacy research. HMB is a metabolite of the amino acid leucine — it is what the body produces naturally when leucine is metabolized, and it is the fraction responsible for leucine's muscle-preserving properties. HMB works through two distinct mechanisms that make it an ideal partner to creatine:
  • It inhibits the ubiquitin-proteasome pathway — the primary system responsible for breaking down muscle protein. By slowing this catabolic process, HMB reduces the muscle tissue breakdown that occurs during and after intense training, particularly during periods of caloric deficit, high training volume, or incomplete recovery.†
  • It stimulates the mTOR pathway — the same anabolic signaling cascade triggered by leucine and insulin — which activates muscle protein synthesis. It also promotes the release of IGF-1 (insulin-like growth factor), supporting further muscle growth signaling on the recovery side of training.†
  Research has shown that combining HMB with creatine monohydrate produces significantly greater lean body mass and strength gains than creatine alone — the two compounds address different phases of the muscle growth equation (ATP fueling and anabolic signaling versus muscle preservation and protein synthesis support), producing additive effects when used together.†
• Vitamin D3 (Cholecalciferol) — 500 IU — Vitamin D3 plays a direct role in muscle protein synthesis by sensitizing the Akt/mTOR signaling pathway — the same pathway HMB activates — creating a synergistic interaction between Vitamin D and HMB that further amplifies muscle protein synthesis rates beyond either compound alone. Research has also shown that HMB and insulin combined with Vitamin D produce greater mTOR activation than any of the three individually. Vitamin D deficiency is prevalent in the general population and particularly in athletes who train primarily indoors — including it at a meaningful dose in a creatine formula reflects Transparent Labs' attention to the full performance picture beyond raw creatine dosing.†
• BioPerine (Black Pepper Extract, 95% Piperine) — 5mg — BioPerine is the patented, standardized piperine extract that inhibits the metabolic enzymes responsible for breaking down other active compounds during digestion, increasing their bioavailability and extending how long they remain active in circulation. Applied to creatine and HMB, BioPerine improves the absorption efficiency of both compounds — a practical inclusion that distinguishes Transparent Labs Creatine HMB from basic creatine powders.†

Frequently Asked Questions About Transparent Labs Creatine HMB

1. Do I need to load creatine and when should I take it?
   Transparent Labs does not recommend loading with Creatine HMB because doing so would lead to excessive daily Vitamin D intake. Loading is also not necessary — muscle creatine stores will reach full saturation within 3-4 weeks of consistent 5g daily dosing without a loading phase. The end result is identical to loading; the only difference is that loading gets there a few days faster. Take one scoop daily, every day including rest days — creatine saturation is a cumulative state maintained by daily intake, not a single-dose effect. For timing, Transparent Labs recommends taking it 30 minutes post-workout on training days and in the morning on rest days, though research suggests timing is less critical than daily consistency.†
2. What specifically does HMB add that creatine alone doesn't cover?
   Creatine primarily addresses the energy production side of performance — more phosphocreatine means more ATP available for high-intensity efforts, which translates to more reps, more sets, and greater training volume over time. HMB addresses what happens to muscle tissue after that training session: it reduces the protein breakdown that follows intense exercise and increases the anabolic signaling that drives muscle protein synthesis during recovery. Creatine makes training harder and more productive. HMB makes recovery more efficient and preserves the muscle you've built. Research directly comparing creatine alone versus creatine with HMB has shown meaningfully greater lean body mass and strength gains in the combined group. They are complementary rather than redundant.†
3. Why is Transparent Labs Creatine HMB more expensive than basic creatine monohydrate?
   Standard creatine monohydrate is one of the cheapest effective supplements available. What you are paying for in Transparent Labs Creatine HMB is the clinical-grade myHMB (not generic HMB, which varies widely in purity and form), BioPerine for enhanced absorption, Vitamin D3 for the synergistic mTOR activation effect, Informed Choice certification and third-party testing, a clean label with no artificial additives, and the research-backed formulation logic connecting all four ingredients. If all you want is 5g of creatine daily, a generic powder works fine. If you want the most complete, bioavailable creatine formula with complementary muscle growth and preservation support, this is the premium option.†
4. Can I take Creatine HMB alongside Transparent Labs Bulk or Bulk Black pre-workout?
   Yes — this is exactly how Transparent Labs designs their stack. Because Bulk Black and the original Bulk contain no creatine (by design, as high caffeine doses may interfere with creatine's ergogenic effects), Creatine HMB is meant to be taken separately, ideally post-workout. The pre-workout handles energy, pump, focus, and performance stimulation. Creatine HMB handles the post-workout recovery, phosphocreatine replenishment, and muscle-building signal amplification. The two products complement each other at the level of mechanism with no ingredient overlap.†

How to Take Transparent Labs Creatine HMB

Mix 1 level scoop with 10-12oz of cold water or any beverage 30 minutes following your workout. On non-training days, take 1 scoop in the morning. Take daily — including rest days — for best results. Creatine requires consistent daily use to maintain muscle saturation. Do not use multiple scoops for loading purposes as this will lead to excessive Vitamin D intake. Drink adequate water throughout the day to support creatine metabolism.†

Other Transparent Labs Products at Get Yok'd

• Transparent Labs Bulk Black Pre-Workout — high-stim pre-workout designed to stack with Creatine HMB post-workout
• Transparent Labs Bulk Pre-Workout — the original Bulk formula, designed as a daily-driver for muscle-building athletes
• Transparent Labs Whey Protein Isolate — grass-fed whey isolate with no artificial additives

Why Buy Supplements at Get Yok'd

• Real-time inventory across all five Southern California stores
• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
• Authorized retailer of Transparent Labs
• One of the best loyalty programs in the supplement industry — earn rewards on every purchase
• Owned and operated by fitness enthusiasts who actually use what we sell

Who Should Not Take Transparent Labs Creatine HMB

• Consult a physician before use if you have pre-existing kidney disease or impaired kidney function
• Consult a physician before use if pregnant, nursing, or taking prescription medications
• Not for use by persons under 18 without physician guidance
• Do not use multiple scoops per day for creatine loading — the Vitamin D content makes high daily doses inappropriate
• Discontinue use 2 weeks before any scheduled surgical procedure
• Keep out of reach of children. Store in a cool, dry place.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.