Transparent Labs Longevity is a four-ingredient healthy aging complex built around the biological systems that research consistently links to healthspan — NAD+ metabolism, mitochondrial energy production, neurogenesis, and antioxidant defense. The formula uses four branded, patented, clinically studied compounds: SIRTality® NMN to promote NAD+ production and support healthy cellular function during aging, MicroActive® CoQ10 for sustained mitochondrial energy and cardiovascular support, PQQ (Pyrroloquinoline Quinone) for cognitive performance and Nerve Growth Factor support, and Theracurmin® — a patented curcumin preparation with 27x greater bioavailability than standard turmeric extract — for antioxidant and inflammatory balance. No proprietary blends. Complete label transparency — all doses disclosed. Third-party lab tested. 60 capsules — 30 two-capsule servings. Take 2 capsules daily, ideally earlier in the day, with or without food. $79.99. California Prop 65 Warning applies.†
Supplement Facts — Transparent Labs Longevity (Per 2 Capsules / 30 Servings)
SIRTality® NMN (Beta-Nicotinamide Mononucleotide) — NAD+ precursor for cellular energy and healthy aging
MicroActive® CoQ10 (Coenzyme Q10, sustained-release) — mitochondrial energy and cardiovascular antioxidant support
PQQ (Pyrroloquinoline Quinone) — Nerve Growth Factor support and cognitive performance
Theracurmin® (Curcuma longa extract, patented) — 27x more bioavailable than standard curcumin powder; antioxidant and inflammatory balance support
No proprietary blends. Complete label transparency — all doses disclosed on label.
Third-party lab tested for purity and potency
Clinically dosed — all four ingredients at doses used in published clinical research
60 capsules — 30 two-capsule servings (30-day supply)
Take 2 capsules daily, ideally earlier in the day, with or without food
Daily use recommended to maintain NAD+ levels and support healthy aging over time
$79.99
Safe for men and women
California Prop 65 Warning applies.
Transparent Labs — Why Their Brand Standard Matters for a Longevity Formula
Transparent Labs built its reputation on a specific commitment: no proprietary blends, no underdosed window-dressing ingredients, and complete label transparency on every product. For a longevity supplement — a category with a significant history of overpromised, underdosed products that use branded ingredient names without providing meaningful doses — Transparent Labs' formulation standards are particularly meaningful. Every dose in Longevity is disclosed on the label, confirmed to match the doses used in published clinical research on each branded compound, and verified through third-party testing. The four ingredients in this formula are not picked for label appeal — they are picked because they address four distinct, well-documented biological mechanisms relevant to healthy aging.†
The Four Compounds — What Each One Does
SIRTality® NMN — Restoring NAD+ for Cellular Energy and Aging Support
NAD+ (Nicotinamide Adenine Dinucleotide) is one of the most important molecules in the body — a coenzyme present in every cell that is essential for mitochondrial ATP synthesis, DNA repair, sirtuin protein activation, and hundreds of other metabolic reactions. NAD+ levels decline progressively with age — research documents that NAD+ levels in humans fall by roughly 50% between the ages of 40 and 60, and this decline is increasingly recognized as one of the primary drivers of age-related metabolic dysfunction, reduced cellular energy, impaired DNA repair, and the biological changes associated with aging.†
NMN (Beta-Nicotinamide Mononucleotide) is a direct precursor to NAD+ — it enters cells via the Slc12a8 NMN transporter and is immediately converted to NAD+ inside the cell, bypassing several of the conversion steps that limit the efficacy of other NAD+ precursors like Niacin and Tryptophan. By replenishing the body's NMN supply, the body receives what it needs to maintain normal NAD+ levels to support healthy cellular function and metabolism during aging. SIRTality® is a branded, stability-enhanced NMN form that Transparent Labs selected specifically for its verified purity and bioavailability profile — NMN quality varies significantly across suppliers, with cheaper sources frequently failing purity verification.†
Sirtuins — the protein deacetylases that NAD+ activates — are specifically relevant to the longevity context. Sirtuins (SIRT1-7) regulate a broad array of processes including mitochondrial biogenesis, inflammation suppression, DNA repair, cell survival signaling, and metabolic regulation. The research on NAD+ precursors and sirtuin activation is among the most active in the longevity science field, with multiple ongoing human clinical trials investigating NMN's effects on aging biomarkers.†
MicroActive® CoQ10 — Sustained-Release Mitochondrial Energy and Antioxidant Support
CoQ10 (Coenzyme Q10, ubiquinone) is a fat-soluble, vitamin-like compound found in the inner mitochondrial membrane of every cell — essential for the electron transport chain that produces ATP. CoQ10 serves two primary roles: as the electron carrier that enables the final steps of mitochondrial ATP synthesis (making it essential for energy production in every cell), and as the primary lipid-phase antioxidant protecting cell membranes and mitochondria from oxidative damage. Like NAD+, CoQ10 levels decline with age — and statin medications (the most widely prescribed class of drugs in the US) specifically deplete CoQ10 by inhibiting the same mevalonate pathway that produces both cholesterol and CoQ10.†
MicroActive® CoQ10 is a patented, microsphere-encapsulated CoQ10 form from Lonza that produces a unique sustained-release absorption profile: approximately 33% of the CoQ10 is released rapidly within the first 2 hours, while the remaining 67% releases slowly over the following 24 hours. Standard CoQ10 supplements produce a single absorption peak that fades within hours — MicroActive® CoQ10's sustained release maintains elevated CoQ10 blood levels throughout the entire day from a single daily dose. Research has specifically documented that MicroActive® CoQ10 is 3x more bioavailable than standard crystalline CoQ10 in a 24-hour period, addressing the fat-solubility and absorption challenges that have historically limited oral CoQ10 supplementation.†
PQQ (Pyrroloquinoline Quinone) — Mitochondrial Biogenesis and Cognitive Performance
PQQ is a redox-active quinone compound found in trace amounts in foods including fermented soybeans, green tea, and human breast milk. It is a potent antioxidant — by some measures more powerful than Vitamin C — and has unique mechanisms in both mitochondrial biology and neurological function that make it a compelling longevity-relevant compound alongside NMN and CoQ10.†
PQQ's most significant documented mechanism is activation of PGC-1alpha — the "master regulator" of mitochondrial biogenesis. While NMN supports existing mitochondrial function through NAD+ replenishment and CoQ10 supports the efficiency of mitochondrial electron transport, PQQ specifically triggers the creation of new mitochondria. More mitochondria per cell means more energy production capacity — a fundamental mechanism of cellular vitality that declines with age as existing mitochondria accumulate oxidative damage and are not fully replaced. PQQ plays a role in brain function by promoting the production of Nerve Growth Factor (NGF), which helps protect neurons from damage and supports the growth of new neural pathways. PQQ was also found to enhance the brain's capacity to adapt to new information and solve complex problems — the cognitive flexibility and processing that constitute meaningful brain health outcomes beyond simple memory measures.†
Theracurmin® — 27x More Bioavailable Curcumin for Antioxidant and Inflammatory Balance
Curcumin — the primary bioactive compound in turmeric — has one of the broadest anti-inflammatory and antioxidant research databases of any plant compound, with documented effects relevant to joint health, cardiovascular function, cognitive protection, and exercise recovery. The fundamental problem with standard curcumin supplementation is bioavailability — curcumin is intensely poorly absorbed from the GI tract in its natural form, with studies consistently showing that the vast majority of ingested standard curcumin passes through the digestive tract unabsorbed.†
Theracurmin® is a patented herbal complex from Theravalues Corporation that uses a specific ultrafine particle technology and glycerin-based dispersion to produce submicron-sized curcumin particles. Human pharmacokinetic trials demonstrate that Theracurmin® yields systemic exposure that is over 27 times more bioavailable than that of standard curcumin powder — making the dose in each capsule of Longevity equivalent to 27x the curcumin from a standard turmeric extract at the same stated amount. Clinical evidence suggests this enhanced absorption enables Theracurmin® to effectively support biological processes, joint integrity, cardiovascular function, cognitive health, and exercise recovery at doses where standard curcumin produces minimal systemic benefit.†
Why These Four Compounds Work Together
NMN, CoQ10, and PQQ work together to support mitochondrial function, helping cells produce and manage energy more efficiently. The synergy is mechanistically specific rather than coincidental. NMN restores NAD+ — the essential coenzyme for all mitochondrial energy reactions and sirtuin activation. CoQ10 (especially in sustained-release MicroActive® form) ensures the electron transport chain operates efficiently throughout the day. PQQ triggers mitochondrial biogenesis — creating new mitochondria to replace those that have deteriorated over time. Theracurmin® provides the antioxidant and anti-inflammatory context that allows all three mitochondrial support mechanisms to operate without the chronic oxidative and inflammatory interference that accelerates aging at the cellular level.†
This four-mechanism approach addresses healthy aging from a more complete angle than any single-ingredient longevity product. A standalone NMN supplement addresses NAD+ replenishment but not mitochondrial electron transport efficiency or new mitochondria creation. A standalone CoQ10 addresses electron transport but not NAD+ production. Longevity addresses all four simultaneously in a single daily two-capsule serving.†
Frequently Asked Questions
How is SIRTality® NMN different from standard NMN?
SIRTality® is a branded, stability-enhanced form of Beta-Nicotinamide Mononucleotide with verified purity. NMN quality varies significantly across supplement suppliers — cheaper sources frequently fail independent purity verification, with some containing as little as 50-70% of their stated NMN content. SIRTality® provides the assurance of a branded ingredient with documented stability and purity verification, ensuring each capsule delivers meaningful NMN content for NAD+ conversion.†Why is MicroActive® CoQ10 better than standard CoQ10?
Standard CoQ10 is a fat-soluble crystalline compound that absorbs poorly and produces a short peak of absorption after ingestion. MicroActive® CoQ10 uses microsphere encapsulation technology to produce sustained-release absorption — 33% releases within the first 2 hours, 67% releases gradually over 24 hours — maintaining elevated CoQ10 blood levels throughout the day from a single dose. Research documents MicroActive® CoQ10 is 3x more bioavailable than standard crystalline CoQ10 over a 24-hour period.†Who should consider taking Longevity?
Longevity is designed for adults who want to proactively support the biological systems associated with healthy aging — particularly cellular energy, cognitive function, and cardiovascular health. Many adults begin using longevity supplements early and proactively to support the core drivers of healthy aging and enhance energy, cognition, and cardiovascular health as part of a long-term wellness strategy. It's also specifically relevant for individuals over 40 (when NAD+ decline accelerates), individuals on statin medications (which deplete CoQ10), and anyone interested in evidence-based aging support.†Can Longevity be taken alongside other Transparent Labs products?
Yes — Longevity is a non-stimulant daily wellness formula with no interactions with Transparent Labs' performance lineup. Transparent Labs specifically recommends pairing it with Creatine HMB (muscle and performance), Greens (gut health and phytonutrients), and their D3+K2 (bone and cardiovascular support) for a complete foundational wellness and performance stack.†
How to Take Transparent Labs Longevity
Take 2 capsules daily, ideally earlier in the day, with or without food. Consistent daily use is recommended to maintain NAD+ levels and support healthy aging processes over time — the benefits of NMN, CoQ10, and PQQ accumulate with consistent use rather than producing acute effects. Store in a cool, dry place. Not for pregnant or nursing women without physician clearance. Consult a physician before use if taking any prescription medications — particularly statins (CoQ10 interactions), blood thinners (curcumin has mild anticoagulant properties), or any medications metabolized by CYP3A4 enzymes (Theracurmin may affect drug metabolism at high doses). California Prop 65 Warning applies.†
Why Buy at Get Yok'd
Real-time inventory across all five Southern California stores
Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
Authorized Transparent Labs retailer — carrying Longevity alongside the full Transparent Labs wellness and performance lineup
Staff who can help you build a complete daily wellness and performance stack incorporating Longevity
One of the best loyalty programs in the supplement industry — earn rewards on every purchase
Who Should Exercise Caution with Longevity
Not for pregnant or nursing women without physician clearance
Individuals taking blood thinners (Warfarin/Coumadin) should consult a physician — Theracurmin's curcumin component has mild anticoagulant activity
Individuals on statin medications should inform their physician of CoQ10 supplementation — while complementary (statins deplete CoQ10), physician awareness is appropriate
Individuals taking medications metabolized by CYP3A4 enzymes should consult a physician — curcumin can inhibit CYP3A4 and affect the metabolism of certain pharmaceuticals
Individuals scheduled for surgery should consult a physician — curcumin's anticoagulant activity is typically recommended to be discontinued before surgery
Individuals with iron deficiency should consult a physician — PQQ has documented interactions with iron absorption at high doses
Consult a physician before use if taking any prescription medications
California Prop 65 Warning applies.
Keep out of reach of children.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.