Revive MD - GI+ v2 - 30 Servings - Unflavored

Revive MD GI+ v2 is a physician-formulated gut lining and GI health powder — a comprehensive, multi-mechanism digestive support formula covering gut lining integrity, prebiotic fiber for healthy gut bacteria, and GI immune function in a single unflavored 5.5g scoop. Per serving: 1,000mg N-Acetyl-Glucosamine, 1,000mg Apple Pectin, 750mg Arabinogalactans, Deglycyrrhizinated Licorice (DGL) Root Extract, Soy and Sunflower Lecithin, Cinnamon Bark Powder, Green Tea Extract, 150mg Vitamin C, and 65mg Potassium. Zero flavoring. Mix into any beverage. Gluten-free. Informed Sport certified — independently tested for over 285 WADA-prohibited substances. 30 servings per container. Co-founded by Dr. Domenic Iacovone, MD, a board-certified physician whose clinical perspective shapes every Revive MD formula. California Prop 65 Warning applies.†

Supplement Facts — Revive MD GI+ v2 (Per 1 Scoop / 5.5g / 30 Servings)

• Vitamin C (as Ascorbic Acid) — 150mg
• Potassium (as Potassium Chloride) — 65mg
• N-Acetyl-Glucosamine — 1,000mg
• Apple Pectin — 1,000mg
• Arabinogalactans (Larch Tree) — 750mg
• Soy Lecithin
• Sunflower Lecithin
• Deglycyrrhizinated Licorice (DGL) (Glycyrrhiza glabra) Root Extract
• Cinnamon (Cinnamomum cassia) Bark Powder
• Green Tea (Camellia sinensis) Leaf Extract

• Unflavored — mixes into any beverage without affecting taste
• Gluten-free. Soy lecithin present — not appropriate for individuals with severe soy protein allergy (soy lecithin is derived from soy but contains minimal soy protein)
• 30 servings per container
• Mix 1 scoop daily in 8-12oz of water, juice, smoothie, or any beverage
• Informed Sport certified — tested for 285+ WADA-prohibited substances every batch
• California Prop 65 Warning applies.

Revive MD — The Physician-Formulated Brand

Revive MD was co-founded by Dr. Domenic Iacovone, MD — a board-certified physician — and elite bodybuilding coach Matt Jansen. The brand's positioning as physician-formulated is not a marketing label attached to a typical supplement company: Dr. Iacovone's clinical background shapes the formulation approach across every product in the Revive MD catalog. The brand occupies the intersection of sports nutrition and functional medicine, producing products that serious athletes use alongside a clinical perspective that general health consumers trust. Revive MD's commitment to full label transparency and Informed Sport testing reflects the same evidence-based, no-guesswork approach to supplementation that characterizes functional medicine at its best.†

Why Gut Health Matters — Especially for Athletes

Gut health is one of the most consequential health dimensions for athletic performance, yet it is systematically under-addressed in most supplement programs. The gastrointestinal tract is not just a food-processing tube — it is the primary interface between the external environment and the body's internal systems, responsible for nutrient absorption efficiency, immune system education (approximately 70-80% of immune cells reside in gut-associated lymphoid tissue), the gut-brain axis that influences mood and motivation, and the integrity of the mucosal barrier that prevents pathogenic compounds from entering systemic circulation.†

Athletes are particularly vulnerable to GI dysfunction for several reasons. High-intensity training redistributes blood flow away from splanchnic (gut) circulation toward working muscles — repeated intense exercise creates ischemia-reperfusion cycles in the intestinal wall that compromise mucosal integrity over time. High protein intakes (common in strength athletes) require robust digestive enzyme activity and adequate gut lining health for efficient absorption. The chronic low-grade inflammation that accompanies heavy training creates oxidative stress in gut tissue. And the supplement loads many athletes carry — prohormones, stimulant fat burners, high-dose amino acids — all create additional metabolic demands on the GI system.†

GI+ v2 addresses the gut health limitations that these specific athlete demands create, through a formula designed to rebuild and maintain gut lining integrity, feed beneficial gut bacteria, and support the mucosal protective layer that is the front line of GI defense.†

The Formula — What Each Compound Does

N-Acetyl-Glucosamine — 1,000mg — Gut Lining Structural Repair

N-Acetyl-Glucosamine (NAG) is the specific glucosamine form used for intestinal mucosa tissue regeneration — and Revive MD's decision to use NAG rather than the glucosamine sulfate common in joint supplements reflects a clinically meaningful distinction. The intestinal mucosal lining is composed largely of glycoproteins (mucins) whose backbone structure incorporates N-acetyl-glucosamine as a primary building block. The epithelial cells lining the intestine turn over completely every 3-5 days, requiring continuous NAG supply to synthesize new mucosal glycoproteins. In individuals with inflammatory bowel conditions, the enzyme that converts standard glucosamine to N-acetyl-glucosamine is less active — meaning supplementing with NAG directly bypasses this conversion bottleneck and provides the substrate the gut lining needs in its ready-to-use form.†

A pilot study published in Alimentary Pharmacology and Therapeutics administered 3-6g of N-acetyl-glucosamine to 12 pediatric patients with severe inflammatory bowel disease unresponsive to conventional treatments. Of the 12 patients, 8 recovered and required no further intervention — a notable outcome for a natural compound in a difficult-to-treat population. At 1,000mg, GI+ v2 delivers a meaningful daily maintenance dose of NAG for gut lining support in healthy individuals.†

Apple Pectin — 1,000mg — Prebiotic Soluble Fiber

Apple Pectin is a soluble dietary fiber extracted from apple pulp that functions as a prebiotic — a non-digestible compound that selectively feeds beneficial gut bacteria. When Apple Pectin reaches the colon undigested, Lactobacillus and Bifidobacterium species ferment it, producing short-chain fatty acids (SCFAs) — particularly butyrate, acetate, and propionate. Butyrate is the primary energy substrate for colonocytes (the cells lining the colon) and is essential for maintaining colonic mucosal integrity, supporting tight junction proteins that prevent intestinal permeability, and modulating the immune response within the colon. Butyrate also has direct anti-inflammatory properties at the epigenetic level through histone deacetylase (HDAC) inhibition — it reduces the expression of inflammatory cytokines in gut tissue.†

Apple Pectin also directly reduces intestinal permeability ("leaky gut") by upregulating the expression of claudin and occludin — the tight junction proteins that seal the spaces between intestinal epithelial cells and prevent paracellular transport of bacteria, toxins, and undigested food particles into the bloodstream. At 1,000mg, GI+ v2 delivers a meaningful prebiotic fiber dose that complements the structural repair work of NAG with ongoing microbiome support.†

Arabinogalactans (Larch Tree) — 750mg — Prebiotic Immune Modulator

Arabinogalactans are long-chain polysaccharides derived from the Larch tree (Larix species) that function as both prebiotic fiber and immune modulators — a dual role that makes them particularly relevant for athletes whose training creates both microbiome disruption and immune challenges. As a prebiotic, arabinogalactans support the same Bifidobacterium and Lactobacillus growth as Apple Pectin while also specifically promoting butyrate-producing bacteria. Their immune-modulating activity is distinct from their prebiotic effects: arabinogalactans interact directly with natural killer (NK) cells, macrophages, and dendritic cells in the gut-associated lymphoid tissue, supporting the innate immune response that is the GI tract's first line of defense against pathogens. Research on larch arabinogalactans has documented improvements in gut microbiome composition, immune function markers, and upper respiratory infection rates in supplemented groups.†

Deglycyrrhizinated Licorice (DGL) Root Extract — GI Soothing and Mucosal Protection

Licorice root (Glycyrrhiza glabra) has been used medicinally for GI complaints for thousands of years across multiple traditional medicine systems. The "deglycyrrhizinated" (DGL) form specifically removes the glycyrrhizin compound — a component of raw licorice that can cause sodium retention, potassium loss, and elevated blood pressure at high doses with chronic use. DGL retains the carbenoxolone precursors and flavonoid compounds responsible for licorice's mucosal protective effects without the glycyrrhizin-associated side effects.†

DGL's primary mechanism is stimulation of mucin secretion — it promotes the secretion of protective mucus from goblet cells in the gastric and intestinal mucosa, increasing the thickness and integrity of the mucous layer that protects the underlying epithelium from gastric acid, digestive enzymes, and pathogenic compounds. Research on DGL has documented improvements in gastric ulcer healing, reduction of gastroesophageal reflux symptoms, and overall GI comfort. DGL also has mild anti-inflammatory effects in gastric tissue through inhibition of arachidonic acid metabolites.†

Soy Lecithin and Sunflower Lecithin — Phosphatidylcholine and Mucosal Barrier Support

The dual lecithin approach in GI+ v2 provides phosphatidylcholine (PC) — the primary phospholipid component of the intestinal mucosal barrier. Phosphatidylcholine forms a protective phospholipid layer over the intestinal mucus that repels water-soluble contents of the intestinal lumen, preventing direct contact between luminal contents and the epithelial cell surface. Research on the intestinal phosphatidylcholine barrier has shown that reduced PC content in the mucus layer is associated with ulcerative colitis and increased intestinal permeability. Supplementing phosphatidylcholine sources (via lecithin) supports the replenishment of this PC layer. Soy Lecithin and Sunflower Lecithin together provide two complementary sources of PC — soy lecithin is the more concentrated source, sunflower lecithin provides a soy-free backup for those with soy sensitivities (though the soy protein content in soy lecithin is minimal).†

Cinnamon (Cinnamomum cassia) Bark Powder — Antimicrobial and Microbiome Balance

Cinnamon's inclusion in a gut health formula is not for flavor — GI+ v2 is unflavored. Cinnamon bark contains cinnamaldehyde and other phenolic compounds with documented antimicrobial activity against pathogenic bacteria (including H. pylori, E. coli, and Candida) without disrupting beneficial Lactobacillus and Bifidobacterium populations. This selective antimicrobial activity is relevant for athletes and high supplement users who may have disrupted gut microbiome balance. Cinnamon also supports gut motility and has mild anti-inflammatory effects in the GI tract.†

Green Tea Leaf Extract — Antioxidant and Anti-Inflammatory GI Support

Green Tea Extract's role in GI+ v2 is its polyphenol content — particularly EGCG (epigallocatechin gallate) — which provides antioxidant protection for intestinal epithelial cells against the oxidative stress of digestion and training-induced gut ischemia-reperfusion. EGCG has documented anti-inflammatory effects in the gut through inhibition of NF-kB signaling — reducing the production of pro-inflammatory cytokines in intestinal tissue. Green tea catechins also have prebiotic-like effects on the gut microbiome, promoting beneficial bacteria while reducing pathogenic populations.†

Vitamin C — 150mg and Potassium — 65mg

Vitamin C at 150mg (167% DV) provides antioxidant support for the gut lining and plays a role in collagen synthesis — collagen is a structural component of the intestinal wall, and adequate Vitamin C is required for the hydroxylation reactions that produce stable collagen. Potassium at 65mg supports smooth muscle function in the GI tract — adequate potassium is necessary for normal GI motility and the muscular contractions that move food through the digestive system.†

GI+ v2 vs. v1 — What Changed

The v2 update refined the formula around the core gut lining and prebiotic ingredients while updating several supporting compounds. The NAG, Apple Pectin, and Arabinogalactan prebiotic core remain consistent from v1. The v2 adds the dual lecithin phosphatidylcholine approach (Soy + Sunflower Lecithin) — a meaningful addition given the research on intestinal phosphatidylcholine barrier integrity. Cinnamon Bark Powder and Green Tea Extract were added in v2 for antimicrobial and antioxidant GI support. The Informed Sport certification was added, making GI+ v2 appropriate for tested athletes who want verified gut health support without banned substance risk.†

Who GI+ v2 Is For

GI+ v2 serves five distinct user profiles. Athletes running heavy supplement stacks — particularly prohormone users and high-stim pre-workout users — whose GI system is under consistent metabolic demand from processing these compounds. Athletes with significant training volume whose repeated intense exercise creates gut ischemia and mucosal compromise over training blocks. Anyone experiencing gut discomfort, bloating, irregular bowel function, or general GI distress who wants a comprehensive, physician-formulated support formula. Individuals with a history of GI inflammation (IBS, gastritis, acid reflux) who want daily support for mucosal integrity. And anyone who simply wants to ensure their gut health infrastructure is optimized for nutrient absorption — since even perfect diet and supplement choices only produce results proportional to how well the GI system can absorb and utilize what's provided.†

Frequently Asked Questions

1. Does GI+ v2 contain soy protein? Is it appropriate for people with soy allergies?
   GI+ v2 contains Soy Lecithin — a phospholipid extract from soybeans that is refined to remove most soy protein. Most people with mild soy sensitivities tolerate soy lecithin well because the allergenic soy proteins are largely removed during processing. However, individuals with severe soy protein allergies (particularly IgE-mediated soy allergy) should consult their physician before using GI+ v2. The formula also contains Sunflower Lecithin as an additional lecithin source.†
2. Why is GI+ v2 a powder rather than capsules?
   The 5.5g serving size requires a powder format — the doses of NAG, Apple Pectin, and Arabinogalactans alone would require 8-10 capsules per serving to match the powder dose. Revive MD's explicit philosophy is that meaningful gut health support requires therapeutic doses of prebiotic fibers and structural support compounds that capsule formats cannot accommodate practically.†
3. Can GI+ v2 be used alongside probiotics?
   Yes — and this is often the recommended approach. GI+ v2's prebiotic fiber components (Apple Pectin, Arabinogalactans) feed beneficial gut bacteria, while probiotics introduce live beneficial bacteria. Taking prebiotics and probiotics together (a synbiotic approach) supports both the population of beneficial bacteria and the food supply they depend on. Take GI+ v2 daily with your probiotic supplement for synergistic gut microbiome support.†
4. Is GI+ v2 safe for tested athletes?
   Yes. Revive MD GI+ v2 is Informed Sport certified — independently tested every batch for over 285 substances prohibited by WADA and major sports governing bodies. It is one of the most rigorously tested gut health supplements available and is appropriate for athletes in any tested sport.†

How to Take Revive MD GI+ v2

Mix 1 scoop (5.5g) in 8-12oz of water, juice, smoothie, or any beverage once daily. Unflavored — adds no taste to any beverage. Can be mixed into protein shakes or morning beverages. For best results, take consistently daily — gut lining repair and microbiome changes are cumulative effects that develop over 4-8 weeks of consistent use. No stimulants. No cycling required — safe for continuous daily long-term use. Not for pregnant or nursing women without physician clearance. Individuals with severe soy allergies should consult a physician before use. Consult a physician before use if taking any prescription medications, particularly immunosuppressants. California Prop 65 Warning applies.†

Why Buy at Get Yok'd

• Real-time inventory across all five Southern California stores
• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
• Authorized Revive MD retailer
• Staff who can help you build a complete gut health and GI support stack in person
• One of the best loyalty programs in the supplement industry — earn rewards on every purchase

Who Should Exercise Caution with GI+ v2

• Individuals with severe soy protein allergies should consult a physician — contains Soy Lecithin
• Not for pregnant or nursing women without physician clearance
• Individuals taking immunosuppressant medications should consult a physician — arabinogalactans and green tea extract modulate immune function
• Individuals with blood sugar regulation issues should be aware that cinnamon can affect blood glucose — consult a physician if on diabetes medications
• Consult a physician before use if taking any prescription medications
• California Prop 65 Warning applies.
• Keep out of reach of children.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.