Hi-Tech Pharmaceuticals L-Glutamine delivers 5g of pure L-Glutamine per scoop in an unflavored powder that mixes into any beverage — 100 servings per container. Glutamine is the most abundant amino acid in human skeletal muscle, comprising more than 60% of its total amino acid content, making it one of the most logical standalone supplements for athletes focused on recovery, gut health, and immune support. Made by Hi-Tech in their cGMP-certified U.S. manufacturing facilities.†
Nutrition Per Serving
- L-Glutamine — 5g per scoop
- 100 servings per container (500g)
- Unflavored — mixes into water, protein shakes, or any beverage
- No added ingredients, no sweeteners, no fillers
What L-Glutamine Does in the Body
- Skeletal muscle support — over 60% of all human skeletal muscle is comprised of glutamine. During intense training, glutamine stores in muscle tissue are significantly depleted. Supplementing post-workout helps replenish those stores and supports the protein metabolism required for muscle repair and growth.†
- Gut barrier integrity — glutamine is the primary fuel source for enterocytes (the cells lining the small intestine) and plays a critical role in maintaining the integrity of the intestinal barrier. This is particularly relevant for high-protein athletes whose digestive systems process significantly greater protein loads than sedentary individuals.†
- Immune function — after synthesis in skeletal muscle, glutamine enters the bloodstream and is transported to the liver, small intestine, kidneys, and cells of the immune system. White blood cells rely heavily on glutamine as a fuel source, and glutamine depletion from intense training has been associated with suppressed immune function. Daily supplementation helps normalize immune system activity during heavy training blocks.†
- Nitrogen shuttling — glutamine is one of the primary vehicles for transporting nitrogen between tissues in the body, playing a central role in protein metabolism and the anabolic environment necessary for muscle repair.†
Frequently Asked Questions About Hi-Tech L-Glutamine
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Why supplement glutamine if the body produces it naturally?
Glutamine is classified as a conditionally essential amino acid — the body can synthesize it on its own under normal circumstances, but during periods of metabolic stress such as intense training, dieting, or contest prep, the rate of glutamine depletion from muscle tissue outpaces the body's ability to produce it. Studies have shown that plasma glutamine levels drop significantly following intense exercise, and this depletion is associated with impaired recovery, reduced immune function, and increased gut permeability. Supplemental glutamine restores circulating levels efficiently and supports the recovery processes that are otherwise limited by depletion.† -
When is the best time to take L-Glutamine?
Post-workout is the most commonly recommended timing — this is when muscle glutamine stores are at their lowest following training-induced depletion, and replenishment during this window supports recovery most directly. A second dose first thing in the morning is also popular for supporting gut health and immune function throughout the day. Some athletes add a dose before bed. Because glutamine is unflavored and water-soluble, it mixes invisibly into a post-workout protein shake without affecting taste or texture, making it easy to combine with the rest of your post-workout routine.† -
How does glutamine support gut health specifically?
The cells lining your small intestine — enterocytes and colonocytes — have exceptionally high energy requirements and rely on glutamine as their primary fuel source rather than glucose. When glutamine availability is low, intestinal cell turnover slows and the tight junctions between cells can become compromised. This is especially relevant for athletes who consume large amounts of protein and put significant demand on the digestive system daily. Consistent glutamine supplementation supports enterocyte energy supply, helping maintain the structural integrity of the gut lining.† -
Is glutamine useful during a cut or contest prep?
Yes — and this is arguably where glutamine is most valuable. During a caloric deficit, the body has a heightened tendency to break down muscle tissue for fuel (catabolism). Glutamine supports protein metabolism and helps preserve muscle nitrogen balance during periods of caloric restriction, making it a staple in contest prep and cutting protocols alongside other anti-catabolic supplements. Hi-Tech specifically calls out improved recovery during dieting and contest prep as a primary use case for their L-Glutamine.† -
Can I stack L-Glutamine with creatine and protein?
Yes — glutamine is fully compatible with creatine, whey protein, BCAAs, and EAAs. It has no known interactions with any common sports supplement. Many athletes mix glutamine directly into their post-workout protein shake for convenience. If you are also using the CBUM Mass Gainer or Revive MD Essential Vitamins Pack, note that both already include glutamine — check doses before adding standalone glutamine on top to avoid unnecessarily high total intakes.†
How to Take Hi-Tech L-Glutamine
Mix 1 scoop (5g) with 8oz of water or your preferred beverage. Stir or shake until dissolved. Best taken post-workout to support muscle recovery, or first thing in the morning to support gut health and immune function. Can be added directly to a protein shake. Use daily for best results — glutamine's benefits accumulate with consistent use rather than single acute doses.
Other Hi-Tech Pharmaceuticals Products at Get Yok'd
- Hi-Tech Pharmaceuticals Creatine Monohydrate — HPLC-verified 99.5% pure, stacks directly with glutamine post-workout
- Hi-Tech Pharmaceuticals Precision EAAs — complete essential amino acid formula for intra and post-workout support
Why Buy Supplements at Get Yok'd
- Real-time inventory across all five Southern California stores
- Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
- Authorized retailer of Hi-Tech Pharmaceuticals
- One of the best loyalty programs in the supplement industry — earn rewards on every purchase
- Owned and operated by fitness enthusiasts who actually use what we sell
Who Should Not Take Hi-Tech L-Glutamine
- Consult a physician before use if pregnant, nursing, or have a pre-existing medical condition
- Individuals with kidney or liver disease should consult their physician before use — high amino acid intake may place additional demand on these organs
- Individuals with a history of seizures should consult their physician before use — glutamine is a precursor to glutamate, an excitatory neurotransmitter
- Keep out of reach of children
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.