Hi-Tech Pharmaceuticals Andriol is a single-ingredient long-ester 4-Andro prohormone — 158mg of Androst-4-en-3β-ol-17-one Undecanoate per tablet — designed as the closest legal alternative to Testosterone Replacement Therapy (TRT) in the dietary supplement category. The undecanoate ester is the defining innovation: a long-chain fatty acid attached to the 4-Androstenolone molecule that enables partial absorption through the gastrointestinal tract into the lymphatic system, bypassing a significant portion of liver first-pass metabolism that destroys most oral prohormone compounds before they reach systemic circulation. This lymphatic absorption pathway is the same mechanism used by pharmaceutical testosterone undecanoate (Andriol Testocaps) — Hi-Tech's supplement replicates this absorption architecture in a legal DHEA-derived compound. The result is meaningfully higher bioavailability than non-esterified 4-Andro products and a slower, more sustained conversion to testosterone that supports longer cycle durations without the aggressive suppression of shorter-ester compounds. 60 tablets per container — 30 days at 2 tablets daily or 60 days at 1 tablet daily. Take with a meal containing fat. Does not need to be cycled — can be taken continuously. PCT (Arimiplex) required when stopping after extended use. Not for women. Men 21+ only. Not for tested athletes. California Prop 65 Warning applies.†
IMPORTANT: Andriol is a 4-Andro (wet) prohormone that converts to testosterone and can aromatize to estrogen. Have Arimistane on hand during any run. PCT with Arimiplex is required when discontinuing after extended use. Not for women. Not for persons under 21. Will cause a positive drug test. Not for tested athletes.
Supplement Facts — Hi-Tech Pharmaceuticals Andriol (Per 1 Tablet)
- Androst-4-en-3β-ol-17-one Undecanoate (4-Androstenolone Undecanoate) — 158mg
- Other Ingredients: Microcrystalline Cellulose, Caprylic Acid, Caproic Acid, Capric Acid, Lauric Acid, Beta Cyclodextrin, Phytosterol, Silica
- Delivery: Fatty acid ester (Undecanoate) + Beta Cyclodextrin — lymphatic absorption pathway
- 60 tablets per container
- Dosing: 1 tablet in the morning with food (60-day supply) OR 1 tablet morning + 1 tablet evening with food (30-day supply)
- Minimum recommended run: 8 weeks. Can be used year-round without cycling.
- PCT: Arimiplex required when stopping — run PCT for half the duration of the cycle
- On-cycle: Have Arimistane (estrogen blocker) on hand — Andriol aromatizes to estrogen
- On-cycle liver support: Liver Rx or Gear Support recommended
- Not for women. Not for persons under 21. Not for tested athletes.
- Will cause a positive drug test.
- California Prop 65 Warning applies.
What Makes Andriol Different — The TRT-Style Prohormone
Every prohormone in Hi-Tech's catalog serves a specific purpose and occupies a distinct position in the product hierarchy. Sustanon 250 is the mass-building powerhouse — four 4-Andro esters plus 3-Beta-Hydroxy in a single tablet, designed for 8-12 week maximum-intensity cycles with aggressive suppression and aggressive gains. Androdiol is pure non-esterified 4-Androstenolone — effective for standard cycle lengths but limited by the lower bioavailability of unesterified oral 4-Andro. Andriol occupies an entirely different category: it is Hi-Tech's TRT-analog product — a single long-ester 4-Andro compound designed to be taken at lower doses for longer durations, providing a sustained, consistent testosterone elevation rather than the aggressive peak-and-trough profile of short-ester cycle compounds.†
Hi-Tech explicitly positions Andriol as their "Testosterone Replenishment Testocaps" — a reference to the pharmaceutical Andriol Testocaps (testosterone undecanoate oral capsules), which use the same lymphatic absorption mechanism to deliver testosterone orally in pharmaceutical TRT protocols. Hi-Tech's dietary supplement version uses 4-Androstenolone Undecanoate — a DHEA-derived legal compound — rather than pharmaceutical testosterone, achieving the same lymphatic delivery pathway for a prohormone compound that still requires enzymatic conversion to testosterone rather than delivering testosterone directly. The distinction between the supplement and the pharmaceutical product is legal and mechanistic — not a claim of pharmaceutical equivalence.†
The Undecanoate Ester — Why This Delivery System Changes Everything
The undecanoate ester is an 11-carbon fatty acid chain attached to the 4-Androstenolone molecule at the 17-position. This esterification fundamentally changes how the compound behaves after oral ingestion. Standard oral prohormones face a brutal first-pass gauntlet: digestive enzymes in the intestine, absorption through the intestinal wall, transit through the portal vein to the liver, and extensive hepatic metabolism before any compound reaches systemic circulation. Most of the active compound is metabolized before it ever reaches the bloodstream — the first-pass effect is what makes most oral prohormones so liver-intensive and so poorly bioavailable.†
The undecanoate ester bypasses this problem through a different absorption pathway. Because undecanoate is a long-chain fatty acid, the Androst-4-en-3β-ol-17-one Undecanoate compound is partially incorporated into lipid micelles in the small intestine — the same fat-digestion structures that absorb dietary fats. These micelles are absorbed by lacteals (lymphatic capillaries in the intestinal villi) rather than by the portal blood system. The lymphatic pathway bypasses the liver entirely — compounds absorbed through the lymphatic system enter the thoracic duct and merge with systemic blood circulation without any hepatic first-pass metabolism. The result is substantially higher bioavailability and significantly less hepatic stress than standard oral prohormone delivery.†
The fat-containing meal requirement is directly connected to this mechanism — dietary fat consumption stimulates the formation of lipid micelles and activates the lymphatic fat absorption pathway. Taking Andriol on an empty stomach reduces the lymphatic absorption fraction, lowering both bioavailability and overall effectiveness. A meal containing moderate fat (15-30g) optimizes undecanoate ester absorption.†
The Conversion Pathway — 4-Androstenolone to Testosterone
Androst-4-en-3β-ol-17-one Undecanoate is the undecanoate ester of 4-Androstenolone (4-DHEA) — a compound that occupies the 4-en position in the steroid backbone (double bond between C4 and C5), distinguishing it from the 1-en position of 1-Andro and the delta-5 position of standard DHEA. After the undecanoate ester is cleaved by esterase enzymes in circulation, free 4-Androstenolone is released. The conversion sequence proceeds through two enzymatic steps: 4-Androstenolone → 4-Androstenedione (via 3β-HSD enzyme) → Testosterone (via 17β-HSD enzyme). Both conversion steps are well-documented and efficient — 4-Andro's two-step conversion to testosterone makes it the most direct testosterone precursor among the legal DHEA-derived prohormones.†
The testosterone produced through this conversion pathway is biochemically identical to endogenous testosterone — it binds androgen receptors with the same affinity, activates the same anabolic and androgenic gene expression programs, and produces the same downstream effects: muscle protein synthesis, nitrogen retention, IGF-1 elevation, bone density support, libido support, mood improvement, and red blood cell production support. Because the end product is testosterone itself (not a modified androgen like 1-Testosterone from 1-Andro), Andriol produces the full-spectrum testosterone profile — including the capacity for aromatization to estradiol, which is why estrogen management with Arimistane on hand is a standard part of the Andriol protocol.†
Andriol vs. Sustanon 250 — Which to Choose
Hi-Tech is explicit about this comparison and addresses it directly in their product positioning. Sustanon 250 delivers four different 4-Andro esters (different chain lengths producing different release kinetics) plus 100mg of 3-Beta-Hydroxy (3-DHEA) — a multi-ester, multi-compound formula designed for maximum anabolic output in a structured 8-12 week cycle. Sustanon 250 will produce larger acute gains in muscle and strength within a given cycle window than Andriol at single-tablet dosing. The tradeoff is intensity of suppression and the mandatory cycling requirement.†
Andriol's undecanoate ester produces a more gradual, sustained testosterone elevation — the long ester releases slowly, avoiding the dramatic spikes and troughs of shorter-ester compounds. This sustained profile is less aggressive in terms of acute suppression, which is why Andriol can be used for 6+ months without requiring mid-cycle PCT the way shorter, more aggressive cycles do. PCT is only required when you decide to discontinue — not on a fixed cycle schedule. For users who want a sustained, year-round testosterone optimization protocol rather than aggressive 8-12 week mass cycles, Andriol is the appropriate choice. For users who want maximum short-cycle anabolic output and are prepared for the corresponding PCT requirements, Sustanon 250 is the stronger choice for that goal.†
Andriol in Stacks — Recommended Combinations
For long-duration users who want to amplify Andriol's testosterone base: Hi-Tech Deca-Durabolin (their 19-Nor/nandrolone-pathway prohormone) stacks with Andriol for up to 8 weeks to add a nandrolone-class anabolic dimension to the testosterone base. This combination covers both the androgen receptor activation from testosterone (via Andriol) and the progesterone-receptor-mediated joint support and muscle recovery of nandrolone (via Deca-Durabolin). After the 8-week stack, Andriol can be continued alone for the long-term protocol.†
For PCT when stopping Andriol after an extended run: Arimiplex is Hi-Tech's recommended PCT compound. Arimiplex contains an aromatase inhibitor (Arimistane), a SERM analog, and natural testosterone support compounds. Run Arimiplex for approximately half the duration of the Andriol cycle — if you ran Andriol for 6 months, run Arimiplex PCT for approximately 3 months. On-cycle liver support with Liver Rx or Gear Support is recommended throughout any extended prohormone protocol.†
Frequently Asked Questions
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Does Andriol really not need to be cycled?
This is Hi-Tech's explicit product positioning and it relates to the undecanoate ester's pharmacokinetics. The long ester produces gradual, sustained testosterone elevation without the aggressive HPG axis suppression that comes from short-ester, high-peak-concentration prohormone compounds. Hi-Tech states Andriol can be taken year-round without cycling for the majority of men. PCT is required only when you decide to stop — not on a fixed cycle schedule. This is the primary behavioral difference between Andriol and other Hi-Tech prohormones that require structured cycle-off-PCT protocols.†
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Does Andriol aromatize? Do I need an estrogen blocker?
Yes — because Andriol converts to actual testosterone, and testosterone aromatizes to estradiol via the aromatase enzyme, estrogen management is appropriate during extended Andriol use. Hi-Tech recommends having Arimistane (their standalone aromatase inhibitor) on hand during the cycle and using it if signs of estrogen elevation appear (water retention, gynecomastia sensitivity, mood changes). Arimiplex (which contains an aromatase inhibitor component) is used for PCT. Having estrogen management available is not optional for an extended testosterone-elevating prohormone protocol.†
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How does the 158mg dose compare to other 4-Andro products?
Hi-Tech notes that Andriol contains 158mg of 4-Andro versus Sustanon 250's 150mg 4-Andro content — Andriol is slightly higher. The meaningful difference is the ester, not the dose: the undecanoate ester's lymphatic absorption pathway delivers more of the stated 158mg to systemic circulation than shorter-ester or non-esterified 4-Andro at equivalent stated doses. Hi-Tech characterizes Andriol as approximately 3x more bioavailable than Androdiol (their non-esterified 4-Andro product) at comparable stated doses.†
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Can Andriol be stacked with Hi-Tech's other prohormones?
For long-term continuous use: stack with Deca-Durabolin for 8 weeks maximum to add the nandrolone-pathway anabolic dimension. For aggressive short cycles: Sustanon 250 stacked with Andriol covers multiple 4-Andro ester profiles simultaneously — this is the more aggressive approach and should not be run for extended durations. For any stack involving multiple prohormone compounds, on-cycle liver support and PCT planning are mandatory, and physician consultation is strongly recommended.†
How to Take Hi-Tech Pharmaceuticals Andriol
Take 1 tablet in the morning with a meal containing fat (15-30g dietary fat optimizes undecanoate ester absorption through the lymphatic pathway). Advanced users: take 1 tablet in the morning and 1 tablet in the evening, each with a fat-containing meal. Minimum recommended run: 8 weeks. Can be continued for 6+ months without cycling. Have Arimistane on hand throughout any Andriol run — use if signs of estrogen elevation appear. On-cycle liver support (Liver Rx or Gear Support) recommended throughout. PCT: Arimiplex, run for half the duration of the cycle, immediately after discontinuing Andriol. Not for women. Not for persons under 21. Not for tested athletes — will cause a positive drug test. Consult a physician before use if taking any prescription medications or having any medical condition. California Prop 65 Warning applies.†
Why Buy at Get Yok'd
- Real-time inventory across all five Southern California stores
- Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
- Authorized Hi-Tech Pharmaceuticals retailer — one of a limited number of authorized specialty retailers for the complete Hi-Tech prohormone lineup
- Staff who can walk you through the full Hi-Tech prohormone catalog, cycle planning, estrogen management, and PCT protocols in person at any location
- One of the best loyalty programs in the supplement industry — earn rewards on every purchase
Who Should Not Take Andriol
- Not for women — for adult men 21 years and older only
- Not for persons under 21 years of age
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Not for tested athletes — Andriol converts to testosterone and DHEA-derived prohormones will cause a positive drug test in all tested athletic environments (WADA, NCAA, USADA, professional sports)
- Not for men with a history of prostate cancer or enlarged prostate without physician clearance — testosterone elevation stimulates prostate tissue
- Not for men with cardiovascular disease, low HDL cholesterol, or high blood pressure without physician clearance — prohormone cycles affect lipid profiles and cardiovascular parameters
- Not for men with liver disease — even with the lymphatic absorption advantage, on-cycle liver support is recommended
- Individuals with hormone-sensitive conditions should not use without physician guidance
- Do not use without an estrogen management plan (Arimistane on hand) and PCT plan (Arimiplex)
- Consult a physician before use if taking any prescription medications
- California Prop 65 Warning applies.
- Keep out of reach of children.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.