Dymatize ISO100 is a 100% hydrolyzed whey protein isolate — the protein has been cross-flow microfiltered to isolate it, then hydrolyzed to pre-break the protein chains into smaller peptides for faster digestion and absorption than any standard whey isolate. 25g protein, 5.5g BCAAs, 2.7g Leucine, 2g carbs, 1g fat, less than 1g sugar, less than 0.5g lactose, approximately 110-120 calories per serving. Gluten free. Informed-Choice certified — every batch tested for banned substances. Made in the USA in GMP-certified facilities. Available in 1.4lb (20 servings) and 5lb (71 servings). Flavors spanning everything from Gourmet Vanilla and Gourmet Chocolate to Fruity Pebbles, Cocoa Pebbles, Birthday Cake Pebbles, Cookies and Cream, Cinnamon Cereal, Salted Caramel, Strawberry, Dunkin' Glazed Donut, Chocolate Peanut Butter, and ISO100 Clear. Contains milk and soy.†
Supplement Facts — Dymatize ISO100 (Per 1 Scoop / ~30g Serving)
- Calories — approximately 110-120 (varies slightly by flavor)
- Total Fat — 0.5-1g
- Total Carbohydrates — 2g
- Sugars — less than 1g
- Protein — 25g
- BCAAs — 5.5g
- Leucine — 2.7g
- EAAs — 11.8g total
- Lactose — less than 0.5g
- Protein Source: Hydrolyzed Whey Protein Isolate + Whey Protein Isolate
- Other Ingredients (vary by flavor): Natural and Artificial Flavors, Salt, Soy Lecithin, Sucralose, Steviol Glycosides (Stevia), Potassium Chloride. Chocolate flavors add Cocoa Powder (Processed with Alkali).
- Contains: Milk and Soy
- Gluten Free. Informed-Choice Trusted by Sport certified. Made in the USA.
- Sizes: 1.4lb (20 servings) / 5lb (~71 servings)
What's Inside ISO100 — Why Hydrolyzed Isolate Is the Top Tier
The Protein Quality Hierarchy — Where ISO100 Sits
There is a meaningful quality difference between whey protein concentrate, whey protein isolate, and hydrolyzed whey protein isolate — and understanding the distinction explains why ISO100 commands its position in the market and why it is priced above standard whey products.†
Whey protein concentrate is the raw form of whey protein produced as a byproduct of cheese manufacturing. Depending on the grade, it contains 70-85% protein by weight with the remainder being lactose, fat, and other milk components. It is the most affordable form of whey and the most commonly used in budget protein powders. It works — but the lactose content creates digestion issues for lactose-sensitive individuals, and the higher fat and carbohydrate content means more calories from non-protein sources per serving.†
Whey protein isolate (WPI) is produced by further filtering whey concentrate through cross-flow microfiltration — a cold-processing method that removes the majority of lactose, fat, and non-protein components while preserving the bioactive protein fractions (lactoferrin, immunoglobulins, beta-lactoglobulin, alpha-lactalbumin). The result is a protein source that is 90%+ protein by weight, with substantially less lactose (making it more suitable for lactose-sensitive individuals), very low fat, and a cleaner macronutrient profile. ISO100 uses cross-flow microfiltration specifically to preserve these bioactive fractions — not all isolation processes do.†
Hydrolyzed whey protein isolate takes the isolate and subjects it to enzymatic hydrolysis — the protein chains are pre-broken down into smaller peptides (di- and tri-peptides) that are absorbed through the intestinal wall more rapidly than intact proteins. Hydrolysis essentially does part of the digestive work before the protein reaches your stomach, shortening the time between consumption and amino acid availability in the bloodstream. For post-workout use specifically — where the window between training and amino acid delivery to recovering muscle matters — hydrolyzed isolate's faster absorption is a genuine performance advantage over standard isolate or concentrate.†
ISO100 uses both hydrolyzed whey protein isolate (listed first — the primary source) and whey protein isolate as secondary — delivering the speed benefit of hydrolysis alongside the purity and bioactive fraction preservation of cross-flow microfiltered isolate. The end result: one of the fastest-absorbing, cleanest-macronutrient, lowest-lactose protein powders available.†
25g Protein, 5.5g BCAAs, 2.7g Leucine — The Numbers That Matter
ISO100's protein count of 25g per serving hits the research-consistent dose range for maximizing muscle protein synthesis from a single protein feeding — the dose at which leucine-triggered mTOR signaling reaches near-maximal activation. The 5.5g BCAA total includes 2.7g of Leucine specifically — Leucine is the individual amino acid most directly responsible for activating the mTOR anabolic pathway, and 2.5-3g of Leucine per dose is the threshold consistently identified in the literature for producing the full anabolic signal. ISO100 meets this threshold in a single serving from the protein alone, before adding any additional EAA or BCAA supplementation.†
The 11.8g total EAAs per serving provides the complete substrate pool that muscle protein synthesis requires — all nine essential amino acids present and available for the synthesis reaction that Leucine's mTOR signal initiates. A protein powder that triggers the signal (Leucine/mTOR) but does not supply the complete EAA substrate pool would leave the anabolic signal under-executed. ISO100's full EAA profile from high-quality whey ensures the synthesis machinery has everything it needs.†
The Lactose and Digestibility Advantage
Less than 0.5g of lactose per serving makes ISO100 appropriate for the large segment of the population with varying degrees of lactose sensitivity — anyone who has experienced bloating, gas, or GI discomfort from standard whey protein concentrate products should try a whey isolate (and specifically a hydrolyzed isolate) before concluding that whey protein doesn't work for them. The digestive issues most people attribute to "whey protein" are almost entirely caused by the lactose in concentrate-based products. ISO100's sub-0.5g lactose content is effectively lactose-free at a practical level.†
The Flavor Program — Why ISO100 Is the Standard for Protein Taste
Dymatize ISO100 maintains one of the most recognized flavor portfolios in the protein category — a combination of its in-house flavors and high-profile licensing collaborations that have made it consistently one of the best-tasting protein powders available at any price point. The Pebbles collaboration with Post Consumer Brands (Fruity Pebbles, Cocoa Pebbles, Birthday Cake Pebbles) reproduces the specific flavor profile of the iconic cereals in protein powder form — something Dymatize's flavor team has executed more accurately than virtually any cereal-inspired protein on the market. The Dunkin' collaboration (Glazed Donut) adds a licensed dessert flavor to the lineup. Core flavors like Gourmet Vanilla and Gourmet Chocolate have been refined over years and remain benchmark standards for what a protein powder should taste like in those categories. ISO100 Clear is a newer format — a lighter, juice-style protein for users who want the ISO100 quality in a non-shake form.†
Frequently Asked Questions About Dymatize ISO100
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How does ISO100 compare to Transparent Labs Grass-Fed Whey or NutraBio Whey?
All three are high-quality isolate-based proteins. The key distinctions: ISO100 uses hydrolyzed whey protein isolate as its primary source — meaning faster absorption than standard (non-hydrolyzed) isolates like Transparent Labs Grass-Fed Whey and NutraBio 100% Whey Protein Isolate. TL Grass-Fed Whey uses cold-processed, grass-fed whey isolate at 28g protein per serving with a cleaner ingredient list (no artificial sweeteners). NutraBio Whey is fully open-label with zero fillers and is third-party tested by Informed-Sport at the same level as ISO100. ISO100's advantage is the hydrolysis speed and the flavor selection. TL and NutraBio's advantage is the grass-fed sourcing and cleaner sweetener profiles. For post-workout use where absorption speed is the priority, ISO100's hydrolysis is a genuine differentiator. For general daily use, any of the three are excellent choices.† -
Can I use ISO100 if I am lactose intolerant?
Very likely yes — ISO100 contains less than 0.5g of lactose per serving, which is well below the threshold that produces symptoms in most lactose-sensitive individuals. The vast majority of people who experience GI issues with standard whey concentrate have no problems with whey isolate. If you have severe clinical lactose intolerance or diagnosed dairy allergy, consult your physician. Note that ISO100 does contain milk protein (whey is derived from milk) and is not appropriate for individuals with a full dairy or milk protein allergy — lactose intolerance and milk protein allergy are different conditions.† -
When is the best time to take ISO100?
Immediately post-workout is the highest-value timing for a hydrolyzed isolate — the rapid absorption gets amino acids to recovering muscle faster than any other protein source. That said, ISO100 works well at any time when dietary protein intake needs to be supplemented: first thing in the morning to stop overnight catabolism, between meals, or as part of a pre-bed protein strategy. Because it is very low in fat and carbohydrates, it does not produce any satiety to speak of — it is a fast-digesting lean protein source rather than a meal replacement.† -
Which flavor is the best seller?
Fruity Pebbles is consistently ISO100's top-selling flavor nationally — the cereal collaboration delivers a spot-on reproduction of the original flavor in protein form that has built a devoted following. Gourmet Chocolate and Gourmet Vanilla are the classic benchmarks that the original customer base returns to. Cocoa Pebbles, Birthday Cake Pebbles, and Cookies and Cream are close behind. The Dunkin' Glazed Donut and Cinnamon Cereal are strong options for users who want something different from the standard chocolate and vanilla protein powder experience. All flavors are available in store — ask our team which ones are in stock at your nearest Get Yok'd location.†
How to Take Dymatize ISO100
Add 1 rounded scoop to 5-8oz of cold water, milk, or your preferred liquid and mix thoroughly — ISO100 is formulated for easy mixing and dissolves cleanly without clumping. For post-workout recovery, consume immediately after training. Can also be used pre-workout, first thing in the morning, or between meals to support daily protein intake goals. ISO100 mixes well in shakers, blenders, or stirred with a spoon. Can be incorporated into high-protein baking and recipes. Use as a food supplement only — do not use as a sole meal replacement.†
Why Buy at Get Yok'd
- Real-time inventory across all five Southern California stores
- Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
- Authorized retailer of Dymatize
- One of the best loyalty programs in the supplement industry — earn rewards on every purchase
- Owned and operated by fitness enthusiasts who actually use what we sell
Who Should Not Take Dymatize ISO100
- Not appropriate for individuals with a milk protein allergy or dairy allergy — ISO100 is derived from whey, a milk protein. Lactose intolerance is a different condition and most lactose-intolerant individuals tolerate ISO100 well.
- Not appropriate for individuals with a soy allergy — contains soy lecithin as an emulsifier
- Not for use as a sole source of nutrition or as a meal replacement program
- Consult a physician before use if you have kidney disease — high-protein diets require adequate renal function
- Keep out of reach of children
- Store in a cool, dry place after opening
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.