Great Supplement!
"Not only do you get your Omega-3s, you get the Coq10 that statins deplete and my wife has come totally off arthritic meds due to the astanthaxin! Works for us, 3 supplements in one!"
Myogenix MyOmega is a three-ingredient premium fish oil formula that goes beyond standard omega-3 supplementation by combining high-concentration Icelandic EPA/DHA with CoQ10 and Astaxanthin — the two compounds that accompany omega-3 fatty acids in nature and that most fish oil supplements remove in processing. Per 3-softgel serving: 1,800mg combined EPA and DHA (600mg per softgel — double the 300mg standard in most fish oil supplements), 60mg CoQ10, and 8mg Astaxanthin. Sourced from premium Icelandic fish oil. No HPMC, Methacrylic Acid Copolymer, Plasacryl, or Triethyl Citrate — none of the enteric coating chemicals found in some fish oil softgels. 90 softgels per container — 30 three-softgel servings. Take 3 softgels daily with meals. Allergens: Contains Milk and Soy. Manufactured in a facility that also processes Wheat and Eggs.†
Myogenix built MyOmega around a specific observation about how EPA and DHA exist in nature. In cold-water fish — salmon, mackerel, sardines, anchovies — EPA and DHA are found alongside two other compounds: Astaxanthin (the carotenoid that gives salmon its orange color, produced by the algae the fish eat) and CoQ10 (the mitochondrial coenzyme essential for producing ATP from the fatty acids the fish metabolize). Standard fish oil supplements strip away both of these co-occurring compounds during the refining and concentration process, leaving only the isolated omega-3 fatty acids. Myogenix's argument is that these compounds exist together in nature for a reason — they are functionally synergistic, not coincidental. MyOmega restores the three-compound profile that isolation processing removes.†
Omega-3 fatty acids EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the two marine-sourced omega-3 fatty acids with the most extensive human clinical evidence base in nutritional science. They are distinguished from plant-sourced ALA (alpha-linolenic acid) — found in flaxseed, chia, and walnuts — by their direct biological activity. While the body can theoretically synthesize EPA and DHA from ALA, it does so extremely inefficiently, meaning marine-sourced EPA/DHA supplementation is the only practical way to significantly increase tissue levels of these fatty acids.†
EPA and DHA serve distinct and complementary physiological roles. EPA is responsible for the majority of omega-3's anti-inflammatory effects — it reduces the body's production of D5D (delta-5-desaturase), the enzyme that converts DGLA to Arachidonic Acid (AA). Arachidonic Acid is the precursor to pro-inflammatory eicosanoids — the signaling molecules that drive inflammation throughout the body. By reducing AA production through D5D inhibition, EPA directly reduces the pro-inflammatory signaling that contributes to chronic low-grade inflammation, joint pain, cardiovascular risk, and the exercise-induced inflammation that slows recovery from training. Research on EPA specifically has documented effects comparable to pharmaceutical antidepressants in clinical depression — a finding that reflects EPA's involvement in brain chemistry and neurotransmitter metabolism.†
DHA is the structural omega-3 — it is the most abundant fatty acid in the brain's gray matter and is a critical structural component of cell membranes throughout the nervous system and retina. DHA levels in brain tissue directly affect membrane fluidity (which governs neurotransmitter receptor function), synaptic transmission efficiency, and cognitive performance. DHA also plays a key role in cardiovascular health through triglyceride reduction, anti-arrhythmic effects on cardiac tissue, and anti-thrombotic activity. Research on DHA supplementation has documented improvements in visual acuity, cognitive function, memory, and reaction time — particularly in older adults and individuals with low baseline DHA intake.†
At 1,800mg combined EPA/DHA per 3-softgel serving — 600mg per softgel — MyOmega delivers double the EPA/DHA of standard fish oil supplements (which typically provide 300mg per softgel). Myogenix notes this directly: "Most fish oil supplements contain 300mg per capsule of combined EPA and DHA. MyOmega contains 600mg per cap, literally twice as much as the leading fish oil supplements." To achieve 1,800mg EPA/DHA from a standard 300mg fish oil supplement requires 6 capsules — MyOmega delivers this in 3.†
The Icelandic sourcing is meaningful from a quality and sustainability perspective. Iceland's cold, clean North Atlantic waters produce fish with naturally high omega-3 concentrations, and Iceland's fishing industry operates under strict sustainability management. Icelandic fish oil is consistently among the most purity-verified sources in the market, with low contamination levels of heavy metals, PCBs, and dioxins compared to fish oil from more industrialized or polluted marine regions.†
Coenzyme Q10 (ubiquinone) is a fat-soluble, vitamin-like compound found in the inner mitochondrial membrane of every cell in the body. It is the essential electron carrier in the mitochondrial electron transport chain — without CoQ10, the final steps of ATP synthesis from all macronutrient sources (carbohydrate, fat, and protein) cannot proceed. CoQ10 is particularly concentrated in tissues with the highest energy demands: the heart, liver, and skeletal muscle. It is also a potent lipid-soluble antioxidant, protecting cell membranes and lipoproteins (including LDL cholesterol) from oxidative damage.†
The connection between CoQ10 and omega-3 supplementation is mechanistically specific. Omega-3 fatty acids (EPA and DHA) are primarily metabolized in the mitochondria through beta-oxidation — the same mitochondrial energy production pathway that requires CoQ10. Myogenix's argument is that supplementing EPA/DHA without adequate CoQ10 creates a bottleneck: the fatty acids are available but the mitochondrial machinery that processes them may be limited by CoQ10 availability, reducing the efficiency of EPA/DHA utilization. By including CoQ10 alongside the EPA/DHA, MyOmega ensures the mitochondrial processing capacity for the omega-3 fatty acids is supported.†
At 60mg per serving, MyOmega provides a meaningful CoQ10 dose. Supplemental CoQ10 has documented efficacy at 100-300mg daily for cardiovascular support in congestive heart failure and hypertension, and at lower doses (30-100mg) for general antioxidant protection and statin-associated myopathy support (statins deplete CoQ10 by inhibiting the mevalonate pathway that produces both cholesterol and CoQ10). The 60mg in MyOmega is positioned as a daily maintenance and synergy dose rather than a therapeutic cardiovascular intervention.†
Astaxanthin is a xanthophyll carotenoid produced by the microalgae Haematococcus pluvialis — the same algae that pink flamingos and salmon consume, giving them their characteristic colors. It is classified as the most potent natural antioxidant ever identified in terms of free radical quenching capacity. Published research documents that Astaxanthin's antioxidant activity is 550 times more potent than Vitamin E, 6,000 times more potent than Vitamin C, and 40 times more potent than beta-carotene — extraordinary figures that reflect Astaxanthin's unique molecular structure allowing it to span the full width of the cell membrane (unlike most antioxidants that work on only one side) and its ability to handle multiple free radical types simultaneously.†
Myogenix specifically highlights the biological logic of combining Astaxanthin with EPA/DHA: in nature, fatty fish that contain EPA/DHA also contain Astaxanthin from their diet. The co-occurrence is not coincidental — Astaxanthin protects the highly polyunsaturated EPA and DHA fatty acids from lipid peroxidation (oxidative damage) in the fish's tissues. The same protective relationship holds in human supplementation: EPA and DHA, being highly unsaturated fatty acids with multiple double bonds, are particularly susceptible to oxidative damage in human tissue. Astaxanthin's powerful lipid-phase antioxidant activity helps protect the EPA and DHA molecules from peroxidation after they've been incorporated into cell membranes — extending their functional lifespan in tissue.†
Clinical research on Astaxanthin has documented multiple independent benefits beyond omega-3 protection: reduction of C-reactive protein (CRP — the primary inflammatory biomarker), improvements in skin elasticity and wrinkle reduction (through UV protection and collagen support), improvements in exercise performance and recovery through reduced exercise-induced oxidative stress, improvements in eye health (the retina contains the highest concentration of DHA of any tissue — Astaxanthin protects this DHA from photo-oxidation), and improvements in sperm quality and male fertility in multiple randomized trials. At 8mg, MyOmega is dosing Astaxanthin at the level used in most positive research outcomes.†
Fish oil quality is fundamentally determined by the source fish species, the marine environment, and the manufacturing process. Icelandic fish oil is produced primarily from North Atlantic cold-water species — typically a combination of mackerel, herring, sardines, and anchovies — that naturally accumulate high concentrations of EPA and DHA due to the cold temperatures of their habitat. The Icelandic fishing industry operates under some of the most stringent environmental management and quality control standards in the world, producing fish oil that consistently tests at the lowest contamination levels for heavy metals (mercury, lead, cadmium), PCBs (polychlorinated biphenyls), and dioxins of any major commercial fish oil source. The molecular freshness of Icelandic fish oil (measured by oxidation markers like peroxide value and anisidine value) is typically superior to fish oil from warmer water or higher-volume fishing regions — fresh, low-oxidation fish oil is meaningfully more bioavailable and less likely to contribute to oxidative stress than rancid or oxidized oil.†
Myogenix makes a specific disclosure that most fish oil brands don't address: MyOmega does not contain Hydroxypropyl Methylcellulose (HPMC), Methacrylic Acid Copolymer, Plasacryl, or Triethyl Citrate. These are enteric coating chemicals used in some "enteric-coated" or "burpless" fish oil capsules to delay the dissolution of the softgel until it reaches the intestine rather than the stomach. The stated rationale for enteric coating is to prevent the fishy taste and burping associated with low-quality fish oil. The unstated consequence is that enteric-coated softgels may not break down efficiently in all individuals — particularly those with impaired gastric acid production (common in older adults and individuals on proton pump inhibitors), potentially reducing the bioavailability of the EPA/DHA content. Myogenix's approach is to use high-quality, low-odor Icelandic fish oil that doesn't require coating chemicals to mask off-putting taste — addressing the quality problem at the source rather than masking it with chemical coatings.†
MyOmega is positioned for active individuals who want comprehensive omega-3, mitochondrial, and antioxidant support in a single daily formula. The five primary benefit categories align with five user profiles. First: athletes and active individuals who want anti-inflammatory support for exercise recovery, muscle soreness reduction, and joint health maintenance — EPA's anti-inflammatory mechanism directly targets the inflammatory cascade that drives post-exercise soreness. Second: cardiovascular health-conscious individuals who want the documented heart health benefits of EPA/DHA plus CoQ10's cardiac-specific mitochondrial and antioxidant support. Third: individuals focused on brain health, cognitive performance, and mood support — DHA's structural role in brain tissue and EPA's antidepressant-level effects in research make this one of the most evidence-backed supplements for brain health. Fourth: eye health and skin health — DHA in the retina and Astaxanthin's UV protection and collagen support address visual and skin aging simultaneously. Fifth: individuals on statins, who are CoQ10-depleted by their medication and who benefit from both the CoQ10 replenishment and the EPA/DHA's complementary cardiovascular support.†
Take 3 softgels daily with meals. Taking with food significantly improves absorption of all three fat-soluble compounds (EPA/DHA, CoQ10, and Astaxanthin) and reduces any potential GI discomfort. Can be split across meals — for example, 1 softgel with each of three daily meals — or taken together with the largest meal of the day. Consistent daily use is required for full benefits: omega-3 fatty acids incorporate into cell membranes over weeks, CoQ10 tissue levels build over weeks of supplementation, and Astaxanthin's antioxidant protection is cumulative. Store in a cool, dry place away from heat and light — omega-3 fatty acids are susceptible to oxidation when exposed to heat, oxygen, and light. Contains Milk and Soy — not appropriate for individuals with milk or soy allergies. Manufactured in a facility that also processes Wheat and Eggs. Not for pregnant or nursing women without physician clearance. Consult a physician before use if taking blood thinners — omega-3 fatty acids have mild anticoagulant activity.†
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Overall rating: 5.0 / 5 from 2 reviews.
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"Not only do you get your Omega-3s, you get the Coq10 that statins deplete and my wife has come totally off arthritic meds due to the astanthaxin! Works for us, 3 supplements in one!"
"Helps it all absorb! Good clean fish oil is a must for any supplement regimen and this is it! I mean THIS is IT!!! Long live Yok’d!"