Hi-Tech Pharmaceuticals Osta-Plex® is a three-compound Cyclosome-delivered prohormone formula marketed as SARM-like — built around 50mg of 19-nor-androst-4-ene-17-one Enanthate (a 19-nor androgen precursor that converts to nandrolone through enzymatic pathways), 250mg of Eucommia Ulmoides 100:1 Bark Extract for joint and connective tissue support alongside androgen receptor activation, and 10mg of Osthole (7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one) — a coumarin derivative studied for anabolic signaling and hormone regulation. Important distinction: Osta-Plex® is a legal dietary supplement prohormone, not a pharmaceutical SARM (Selective Androgen Receptor Modulator) compound like Ostarine (MK-2866), RAD-140, or LGD-4033 — those are unapproved drugs, not dietary supplements. Osta-Plex® is positioned for lean, dry muscle gains without estrogen conversion and without DHT-related side effects — the 19-nor structure does not aromatize to estrogen meaningfully and does not convert to DHT. PCT required: Arimiplex (4 weeks post-cycle). Cycle: 8 weeks on, 6-8 weeks off. Not for women. Men 21+ only. Will cause a positive drug test. Not for tested athletes. California Prop 65 Warning applies.†
WARNING: Osta-Plex® is a 19-nor prohormone — not a natural testosterone booster. PCT with Arimiplex is required after every cycle. Will cause a positive drug test in all athletic testing environments. Not for women of any age. Not for persons under 21. Consult a physician before use.
Supplement Facts — Hi-Tech Pharmaceuticals Osta-Plex® (Per 1 Tablet / 60 Servings)
19-nor-androst-4-ene-17-one Enanthate — 50mg (19-nor prohormone — nandrolone precursor via enzymatic conversion)
Eucommia Ulmoides 100:1 Extract (Bark) — 250mg (androgen receptor activating botanical — joint, connective tissue, and bone support)
7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one (Osthole) — 10mg (coumarin derivative for anabolic signaling and hormone regulation)
Other Ingredients: Microcrystalline Cellulose, Phosphatidylcholine 75%, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Red #40
Delivery: Cyclosome Technology (HPBCD + Phosphatidylcholine 75%) — liposomal lymphatic absorption, bypasses liver first-pass
60 tablets per container
Take 1 tablet in the morning and 1 tablet in the evening
Do not exceed 4 tablets in any 24-hour period
Cycle length: 8 weeks on, 6-8 weeks off
PCT required: Arimiplex — run 4 weeks immediately post-cycle
On-cycle liver support: Liver Rx or Gear Support recommended
Estrogen conversion: minimal — 19-nor structure has low aromatization potential
DHT conversion: does not convert to DHT
Hair loss risk: low — no DHT pathway
Not for women of any age. Not for persons under 21.
Will cause a positive drug test. Not for tested athletes.
California Prop 65 Warning applies.
What Osta-Plex® Is — And What It Isn't
Hi-Tech Pharmaceuticals markets Osta-Plex® with "SARM" language — "Legal Gear (SARM)" and "Selective Androgen Receptor Modulator" positioning. This requires an important clarification for customers who may be familiar with pharmaceutical SARMs from research chemical circles. Pharmaceutical SARMs like Ostarine (MK-2866), LGD-4033 (Ligandrol), RAD-140 (Testolone), and S23 are unapproved drug substances — they are not legal for human consumption as dietary supplements and are explicitly prohibited by WADA, FDA, and most sport governing bodies. Osta-Plex® does not contain any of these compounds. Osta-Plex® is a legal dietary supplement built around a 19-nor prohormone (nandrolone precursor) and botanical compounds that work through androgen receptor-mediated pathways — SARM-like in concept, legal prohormone in formulation.†
The Three Compounds — Mechanism and Function
19-nor-androst-4-ene-17-one Enanthate — 50mg — The 19-Nor Prohormone
19-nor-androst-4-ene-17-one Enanthate is the enanthate-esterified form of 19-norandrostenedione — a 19-nor androgen precursor that converts to nandrolone (19-nortestosterone) through enzymatic reduction in the body. The "19-nor" designation means the compound lacks the carbon-19 methyl group present in testosterone — this structural modification gives 19-nor compounds their characteristic properties compared to testosterone-derived prohormones. The enanthate ester (the same ester used in pharmaceutical nandrolone decanoate formulations) extends the release and activity duration of the active compound through slower esterase-mediated hydrolysis compared to unesterified versions.†
Nandrolone (the active conversion product) is one of the most studied anabolic steroids in sports pharmacology — it has a high anabolic-to-androgenic ratio (approximately 125:37 versus testosterone's 100:100 reference), meaning it produces anabolic muscle building and recovery effects with relatively lower androgenic side effects (acne, hair loss, virilization). Nandrolone is specifically known for its joint-protective effects — it increases synovial fluid production and supports collagen synthesis in connective tissue, making it popular among strength athletes dealing with joint discomfort during heavy training. It does not aromatize to estrogen efficiently (converting instead to the much weaker estrogen estradiol via a different aromatase pathway) and does not convert to DHT (instead reducing to dihydronandrolone, a weaker androgen than DHT with much lower androgenic receptor affinity). These properties produce lean muscle gains without the water retention of testosterone aromatization and without the hair loss risk of DHT.†
Eucommia Ulmoides 100:1 Bark Extract — 250mg — The Botanical Androgen Receptor Activator
Eucommia Ulmoides (Du Zhong) is a traditional Chinese medicinal tree whose bark has been used for over 2,000 years for joint, bone, and connective tissue support. In the context of Osta-Plex®, Eucommia Ulmoides goes beyond common testosterone booster mechanisms. It provides compounds to the body that can activate androgen receptors unlike other testosterone boosters available today — its active constituents (chlorogenic acid, genipin, aucubin) have documented androgen receptor binding activity alongside their traditional applications for connective tissue and bone health. The 100:1 extraction ratio means 250mg of this extract represents 25,000mg of raw bark material concentrated — a significantly more potent form than raw botanical powder. The Eucommia extract's connective tissue and bone support dimension complements the 19-nor prohormone's joint-protective nandrolone activity, producing a product with dual muscle and joint anabolic support.†
Osthole (7-methoxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one) — 10mg — The Coumarin Anabolic Signal
Osthole is the primary bioactive coumarin compound found in Cnidium Monnieri seed — it is a naturally occurring compound with documented estrogenic, androgenic, and anabolic signaling properties. Research on Osthole has identified multiple relevant mechanisms: inhibition of PDE-5 (the same enzyme inhibited by pharmaceutical erectile dysfunction medications, suggesting effects on NO-mediated vascular function), AMPK activation (anabolic and metabolic signaling), and direct androgen receptor interaction. At 10mg per tablet, Osthole contributes the third anabolic signaling dimension alongside the 19-nor prohormone conversion and the Eucommia androgen receptor activation — providing hormonal diversity rather than relying on a single pathway.†
The Lean Gains Profile — Dry Muscle Without Water Retention
Osta-Plex® is specifically positioned for dry, lean muscle gains — the physique-building goal that distinguishes it from the wet bulk orientation of testosterone-converting prohormones like Sustanon 250 or Andriol. The 19-nor compound's minimal aromatization means minimal estrogen-driven water retention. The absence of DHT conversion means no DHT-related androgenic concerns. The result is muscle fullness, hardness, and strength from the nandrolone conversion alongside the joint protection that makes heavy training more sustainable — without the soft, watery appearance of estrogen-elevated water retention. Osta-Plex® is Hi-Tech's recommendation for recomping, lean bulking, and cutting phases where maintaining or building lean mass is the goal alongside body composition improvement.†
Cyclosome Technology — Delivering the 19-Nor Compound Past the Liver
The 19-nor-androst-4-ene-17-one Enanthate in Osta-Plex® faces the same first-pass hepatic metabolism challenge as other oral prohormones — a significant fraction of an unprotected oral dose would be metabolized by liver enzymes before reaching systemic circulation. Cyclosome Technology (HPBCD + Phosphatidylcholine 75%) encapsulates the compound in a cyclodextrin-liposomal complex that absorbs through the intestinal lymphatic system (lacteals) rather than the portal blood system, bypassing liver first-pass metabolism and delivering intact 19-nor compound directly to systemic circulation for conversion to nandrolone in peripheral tissue. The enanthate ester further extends activity through slow enzymatic hydrolysis of the ester bond — providing sustained nandrolone release compared to the faster-clearing un-esterified 19-norandrostenedione.†
Osta-Plex® in the Hi-Tech Prohormone Stack
Osta-Plex® occupies the lean gains and recomp position in Hi-Tech's prohormone catalog. Where Sustanon 250 is the maximum wet bulk formula and Halotestin is the strength and power formula, Osta-Plex® is specifically for athletes who want lean, dry, hard muscle without the water retention, estrogen elevation, or DHT concerns of testosterone-pathway prohormones. Stacking Osta-Plex® with Hi-Tech Anavar is one of the most frequently recommended stack combinations — Anavar's 6,17-keto and lean mass compounds complement Osta-Plex's nandrolone-pathway gains for a comprehensive lean muscle and vascularity stack. On-cycle liver support (Liver Rx or Gear Support) is recommended throughout. PCT with Arimiplex is required immediately post-cycle.†
Frequently Asked Questions
Is Osta-Plex® the same as pharmaceutical Ostarine (MK-2866)?
No. Ostarine (MK-2866) is a pharmaceutical SARM developed by GTx Inc. — an unapproved drug substance that is not legal as a dietary supplement and is prohibited by WADA. Hi-Tech Osta-Plex® does not contain Ostarine or any pharmaceutical SARM compound. Osta-Plex® is a legal dietary supplement built around 19-nor-androst-4-ene-17-one Enanthate (a 19-nor prohormone), Eucommia Ulmoides extract, and Osthole — SARM-like in marketing positioning and androgen receptor-selective mechanism, but a different category entirely from pharmaceutical SARMs.†
Does Osta-Plex® cause hair loss?
Hair loss risk from Osta-Plex® is low compared to testosterone-derived prohormones. The 19-nor structure does not convert to DHT (dihydrotestosterone) — it converts instead to dihydronandrolone, a compound with significantly weaker androgenic receptor affinity than DHT and minimal scalp androgen receptor stimulation. Hair loss from prohormones is primarily driven by DHT pathway activation, which Osta-Plex®'s 19-nor mechanism does not produce.†
Will Osta-Plex® cause a positive drug test?
Yes. 19-nor compounds (nandrolone precursors and nandrolone itself) are among the most reliably detected in athletic drug testing — nandrolone metabolites persist in urine for extended periods and are specifically screened in all WADA and NCAA testing panels. Not for tested athletes under any circumstances.†
Does Osta-Plex® require PCT?
Yes. 19-nor compounds suppress natural testosterone production through HPG axis feedback — the nandrolone conversion suppresses LH and FSH output from the pituitary, reducing testicular testosterone synthesis. PCT with Arimiplex for 4 weeks immediately post-cycle is required to restore natural testosterone production. On-cycle liver support (Liver Rx or Gear Support) is also recommended throughout the cycle.†
How to Take Hi-Tech Pharmaceuticals Osta-Plex®
Take 1 tablet in the morning and 1 tablet in the evening. Can be taken with or without food. Do not exceed 4 tablets in any 24-hour period. Cycle length: 8 weeks on, followed by 6-8 weeks off. PCT: Begin Arimiplex the day after the last Osta-Plex® tablet. Run Arimiplex for 4 weeks. On-cycle liver support: Take Liver Rx or Gear Support throughout the cycle. Not for women of any age. Not for persons under 21. Not for tested athletes — will cause a positive drug test. Consult a physician before use if taking any prescription medications or having any medical condition. California Prop 65 Warning applies.†
Why Buy at Get Yok'd
Real-time inventory across all five Southern California stores
Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
Authorized Hi-Tech Pharmaceuticals retailer — carrying Osta-Plex® alongside the full Hi-Tech prohormone lineup
Staff who can walk you through Osta-Plex® cycle planning, stacking options, on-cycle support, and PCT in person at any location
One of the best loyalty programs in the supplement industry — earn rewards on every purchase
Who Should Not Take Osta-Plex®
Not for women of any age
Not for persons under 21 years of age
Not for tested athletes — 19-nor compounds and nandrolone metabolites are detected in all WADA, USADA, and NCAA drug testing panels. Will cause a positive drug test.
Not for men with prostate cancer or enlarged prostate without physician clearance
Not for individuals with cardiovascular conditions, low HDL, or elevated blood pressure without physician clearance — 19-nor compounds affect lipid profiles
Not for individuals with liver disease — on-cycle liver support is required
Do not use without PCT (Arimiplex) and on-cycle support (Liver Rx or Gear Support) in place
Consult a physician before use if taking any prescription medications
Do not exceed recommended dose or cycle length
California Prop 65 Warning applies.
Keep out of reach of children.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.