Hi-Tech Pharmaceuticals Sustanon 250 is a one-of-a-kind bulking prohormone — the most anabolically potent, single-dose tablet ever created, delivering 11 probolic agents including nine legal prohormone esters at a combined 250mg anabolic compound load per tablet. The formula centers on 150mg of four distinct esters of 4-Androstene-3β-ol,17-one (4-Andro) — a precursor that converts to 4-Androstenediol and then 4-Androstenedione before converting to testosterone through a two-step process, delivering the highest dose of 4-Andro found anywhere in a single tablet. This is paired with 100mg of 3β-Hydroxy-5α-Androstan-17-one, a naturally-occurring 5-alpha-reductase-derived compound that converts to DHT (five times as androgenic as testosterone) and adds a "dry" (non-aromatizing) anabolic layer specifically to deliver strength and lean mass gains without the water retention that pure 4-Andro alone would produce. Non-methylated, so not hepatotoxic — though 4-Andro does slightly aromatize to estrogen, making an aromatase inhibitor advisable after cycling. Delivered via Cyclosome® Technology for maximum bioavailability. Take 1 tablet daily, preferably with a meal. Do not exceed 2 tablets per day. Cycle for 8 weeks followed by PCT (Arimiplex commonly used). Not for women. Men 21+ only. Will cause a positive drug test. California Prop 65 Warning applies.†
Supplement Facts — Hi-Tech Pharmaceuticals Sustanon 250 (Per 1 Tablet)
4-Androstene-3β-ol,17-one (4-Andro) — 150mg, delivered across four distinct ester forms for staggered release and extended activity duration
3β-Hydroxy-5α-Androstan-17-one — 100mg (naturally occurring 5-alpha-reductase-derived compound, converts to DHT)
Total anabolic compound load: 250mg per tablet
Other Ingredients: Microcrystalline Cellulose, Phosphatidylcholine 75%, Hydroxypropyl Beta Cyclodextrin (HPBCD), Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Red #40
Delivery: Cyclosome® Technology (HPBCD + Phosphatidylcholine 75%) — liposomal lymphatic absorption, bypasses hepatic first-pass
Non-methylated — not hepatotoxic
4-Andro slightly aromatizes to estrogen — AI use suggested after cycling
Take 1 tablet daily, preferably with a meal
Do not exceed 2 tablets per day
Cycle length: 8 weeks (60 days) on, followed by PCT (30 days) and 6-8 weeks off before repeating
On-cycle liver support recommended (Liver Rx or Gear Support), despite non-methylated status
Not for women of any age. Not for persons under 21.
Will cause a positive drug test. Not for tested athletes.
California Prop 65 Warning applies.
The Two-Compound Architecture — Bulk Plus Dryness
Sustanon 250's formula is built around a specific strategic pairing: 4-Andro provides the bulk, mass, and fullness that testosterone-pathway prohormones are known for, while the 3β-Hydroxy-5α-Androstan-17-one component provides a "dry" counterbalance that limits the water retention 4-Andro alone would otherwise produce. This combination is what separates Sustanon 250 from a single-compound 4-Andro product — the goal is strength and lean mass gains without the bloated, waterlogged look that pure testosterone-precursor prohormones commonly cause when run alone.†
4-Andro — 150mg Across Four Esters — The Bulking Anchor
4-Androstene-3β-ol,17-one (4-Andro) is a precursor to 4-Androstenediol, which itself converts to 4-Androstenedione — a direct precursor to testosterone. Through this two-step conversion process, 4-Andro ultimately becomes testosterone in the body, driving the muscle fullness, strength gains, and size gains that make 4-Andro a staple bulking compound across the prohormone category. Sustanon 250 delivers 150mg of 4-Andro split across four distinct esters — mirroring the multi-ester design philosophy of the pharmaceutical testosterone blend the product borrows its name from. Different esters carry different numbers of carbon atoms, affecting oil solubility and the rate at which the ester bond is cleaved by esterase enzymes in the body — esters with more carbon atoms tend to release more slowly, meaning the four-ester blend is designed to stagger absorption and extend the compound's activity window across the day rather than delivering a single sharp release and rapid clearance.†
3β-Hydroxy-5α-Androstan-17-one — 100mg — The Dry, DHT-Converting Compound
3β-Hydroxy-5α-Androstan-17-one is naturally produced in the body by the 5-alpha-reductase enzyme — the same enzyme responsible for converting testosterone into DHT. When taken orally, this compound converts slightly to dihydrotestosterone, which is five times as androgenic as testosterone, making it efficient at increasing lean muscle mass, muscle hardness, strength, and aggression. Because this compound does not aromatize to estrogen, it is considered "dry" — its inclusion at 100mg is specifically what allows Sustanon 250 users to gain strength and lean mass without experiencing the water retention that a pure 4-Andro product running at a comparable total anabolic dose would produce.†
Cyclosome® Technology — Delivering 250mg Past First-Pass Metabolism
Both compounds in Sustanon 250 face the same first-pass hepatic metabolism challenge common to oral prohormones — a significant fraction of an unprotected oral dose is metabolized by liver enzymes before reaching systemic circulation. Cyclosome® Technology (HPBCD cyclodextrin complexation plus Phosphatidylcholine 75% liposomal encapsulation) protects the compound and facilitates absorption through the intestinal lymphatic system (lacteals) rather than the portal blood system, bypassing first-pass hepatic metabolism and delivering more intact 4-Andro and 3β-Hydroxy-5α-Androstan-17-one to systemic circulation per tablet than conventional prohormone tablets achieve.†
Non-Methylated — Why This Matters for Liver Safety
Sustanon 250's compounds are non-methylated, meaning they are not hepatotoxic in the way that older-generation methylated prohormones (common in the pre-2014 DASCA-regulated era) were. This is a meaningful safety distinction within the prohormone category — methylation was historically added to oral steroid compounds to protect them from being destroyed by first-pass liver metabolism, but this same methylation was directly responsible for the liver strain and elevated liver enzyme markers associated with older prohormone products. Non-methylated compounds like those in Sustanon 250, especially when paired with Cyclosome® Technology's lymphatic bypass of first-pass metabolism, carry a substantially reduced liver burden — though on-cycle liver support (Liver Rx or Gear Support) remains a sensible precaution given the sustained hormonal load any prohormone cycle places on the body.†
Frequently Asked Questions
Why is it called "Sustanon 250"?
The name borrows from the pharmaceutical testosterone blend Sustanon 250, which combines four testosterone esters at a combined 250mg per injection. Hi-Tech's version mirrors this naming convention and multi-ester design philosophy — 150mg of 4-Andro across four esters plus 100mg of 3β-Hydroxy-5α-Androstan-17-one totals 250mg of combined anabolic compound per tablet.†
Do I need PCT after running Sustanon 250?
Yes. Testosterone-pathway prohormones suppress natural testosterone production through HPG axis feedback. PCT is required immediately following the cycle — Hi-Tech Arimiplex is commonly used for 30 days following an 8-week (60-day) Sustanon 250 cycle.†
Can Sustanon 250 be stacked with other Hi-Tech 4-Andro prohormones (like Brutal 4ce)?
This is not recommended. Both Brutal 4ce and Sustanon 250 deliver concentrated 4-Andro prohormones; combining them doubles your 4-Andro intake and sharply raises the risk of estrogen conversion, water retention, and blood pressure spikes. Choose one 4-Andro source per cycle rather than stacking two.†
Did the formula change when it moved from a carton box to a bottle in 2024?
No — Hi-Tech redesigned the packaging from a carton box to a bottle in 2024, but the formula itself remains exactly the same.†
How to Take Hi-Tech Pharmaceuticals Sustanon 250
Take 1 tablet daily, preferably with a meal. Do not exceed 2 tablets per day — studies show doses under 300mg combined don't reliably yield results, and most users report needing the full 2-tablet dose to notice significant benefit; however, always start conservatively and assess personal tolerance first. Cycle for 8 weeks (60 days), followed by PCT (Arimiplex, 30 days) and a 6-8 week break before repeating. On-cycle liver support (Liver Rx or Gear Support) is recommended throughout the cycle. Consider an aromatase inhibitor (such as Arimistane) given 4-Andro's slight aromatization potential. Not for women of any age. Not for persons under 21. Not for tested athletes — will cause a positive drug test. Consult a physician before use if taking any prescription medications or having any medical condition. California Prop 65 Warning applies.†
Why Buy at Get Yok'd
Real-time inventory across all five Southern California stores
Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
Authorized Hi-Tech Pharmaceuticals retailer — carrying Sustanon 250 alongside the full Hi-Tech prohormone lineup and all on-cycle and PCT support products
Staff who can walk you through Sustanon 250 cycle planning, stacking cautions, on-cycle support, and PCT in person at any location
One of the best loyalty programs in the supplement industry — earn rewards on every purchase
Who Should Not Take Sustanon 250
Not for women of any age
Not for persons under 21 years of age
Not for tested athletes — will cause a positive drug test in all WADA, USADA, and NCAA testing panels
Not for men with prostate cancer, enlarged prostate, or a family history of prostate conditions without physician clearance
Not for individuals with cardiovascular conditions, high blood pressure, or elevated cholesterol without physician clearance
Not for individuals with liver disease — on-cycle liver support is strongly recommended despite non-methylated status
Do not use without PCT (Arimiplex) in place following the cycle
Do not stack with other 4-Andro-containing prohormones (e.g., Brutal 4ce) — doubles estrogen conversion and water retention risk
Consult a physician before use if taking any prescription medications
Do not exceed recommended dose or cycle length
California Prop 65 Warning applies.
Keep out of reach of children.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.