Hi-Tech Pharmaceuticals - Estrogenex Depot - 90 Tablets

Hi-Tech Pharmaceuticals Estrogenex Depot is a natural aromatase inhibitor and estrogen blocker built around a 625mg proprietary blend of 12 ingredients — the strongest, most estrogen-focused formula in Hi-Tech's Estrogenex line. Anchored by Brassaiopsis Glomerulata Extract (containing 13 isolated estrogen-modulating compounds) and 8-Bromo-7-Methoxychrysin (widely regarded as one of the most popular and effective aromatase inhibitors available, working by stopping the conversion of testosterone into estrogen), the formula also includes Epiandrosterone, which converts to DHT and helps shed water weight, giving muscles a firmer, tighter look. Rounding out the blend: 7,8-Benzoflavone, 9-Hydroxy-Alpha-Naphthoflavone, Coumesterol Dimethyl Ether, Indole-3-Carbinol, Beta-Sitosterol, Stinging Nettle Extract, Muira Puama, and the bioavailability-enhancing Naringen. Estrogenex Depot naturally reduces estrogen while maintaining a healthy testosterone-to-estrogen ratio and inhibiting the conversion of testosterone into estrogen — perfect for use on-cycle or as PCT. Take 1 tablet 1-3 times daily with meals. Do not exceed 6 tablets per day. Use for 30 days, followed by at least 30 days off before starting another cycle.†

Supplement Facts — Hi-Tech Pharmaceuticals Estrogenex Depot (Per 1 Tablet)

Proprietary Blend — 625mg

• Brassaiopsis Glomerulata Extract (Leaves) — contains 13 isolated estrogen-modulating compounds, regulates circulating estrogen so testosterone can stay elevated without harsh side effects

• N-Benzoyl-L-Phenylalanine Methyl Ester

• 7,8-Benzoflavone

• 8-Bromo-7-Methoxychrysin ("8-Bromo") — one of the most popular and effective aromatase inhibitors, stops conversion of testosterone into estrogen

• Epiandrosterone (Epi-Andro) — converts to DHT, prevents estrogen conversion, sheds water weight for a firmer, tighter physique

• 9-Hydroxy-Alpha-Naphthoflavone

• Coumesterol Dimethyl Ether

• Indole-3-Carbinol — promotes conversion of estrogen to less potent metabolite forms

• Beta-Sitosterol

• Stinging Nettle Extract (standardized to 3,4-Divanillyltetrahydrofuran and Silica)(Leaves) — supports estrogen modulation and free testosterone; also supports bone/teeth strength and healthy urination

• Muira Puama 20:1 Extract (Root) — traditional vitality-supporting botanical

• Naringen (Fruit) — bioavailability enhancer

• Other Ingredients: Dextrose, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Sodium Starch Glycolate, Starch, Triacetin, Titanium Dioxide, Silica, FD&C Red #3, FD&C Yellow #6

• Individual ingredient doses within the 625mg blend not separately disclosed — proprietary blend format

• 90 tablets per bottle

• Take 1 tablet 1-3 times daily with meals

• Do not exceed 6 tablets per day

• Use for 30 days, then take at least 30 days off before starting another cycle

• Can be used on-cycle or as PCT

• May cause a positive drug test

• California Prop 65 Warning applies.

Brassaiopsis Glomerulata — 13 Estrogen-Modulating Compounds in One Botanical

Brassaiopsis Glomerulata Extract is the lead ingredient in the blend — sourced from a plant containing around 13 isolated estrogen-blocking compounds. This ingredient helps regulate the amount of estrogen circulating in the body at any given time, so as testosterone increases (whether naturally or from a prohormone cycle), this botanical helps keep it elevated without the harsh estrogen-related side effects that commonly accompany rising testosterone.†

8-Bromo — The Category's Most Popular Aromatase Inhibitor

8-Bromo-7-Methoxychrysin, commonly known simply as "8-Bromo," is by far the most popular and effective aromatase inhibitor in this category. It works by directly stopping the conversion of testosterone into estrogen — keeping testosterone levels high, which in turn helps build more muscle and increase strength. This compound is the primary reason Estrogenex Depot is positioned as Hi-Tech's strongest estrogen-blocking formula, compared to the milder botanical approach of Estrogenex 2nd Generation.†

Epiandrosterone — Shedding Water Weight Through DHT Conversion

Epiandrosterone (Epi-Andro) converts to DHT in the body, which then prevents further estrogen conversion — the practical result is that users begin shedding water weight and their muscles start looking firmer and tighter. This is the same mechanistic family found in Hi-Tech's standalone Dymethazine product, here included at a smaller inclusion within a broader estrogen-management blend rather than as a standalone high-dose compound.†

Indole-3-Carbinol, Coumesterol Dimethyl Ether, and Beta-Sitosterol — The Supporting Estrogen Pathway Layer

Indole-3-Carbinol promotes the conversion of estrogen to its less potent, less biologically active metabolite forms — helping reduce the overall downstream effects of circulating estrogen without eliminating it entirely. Coumesterol Dimethyl Ether and 9-Hydroxy-Alpha-Naphthoflavone add additional estrogen receptor and aromatase-pathway modulation. Beta-Sitosterol, a plant sterol, rounds out the formula with its own documented hormone-supportive research.†

Stinging Nettle Extract — A Two-Pathway Ingredient

Stinging Nettle Extract, standardized to 3,4-Divanillyltetrahydrofuran and Silica, is included because it provides two complementary pathways involving estrogen modulation and free testosterone. Beyond its hormone-related activity, Stinging Nettle is also traditionally used to help improve bone and teeth strength, may increase muscle strength and quality, and is found in medicine used for urination problems related to enlarged prostate — helping decrease inflammation and increase urine output, a meaningful secondary benefit for the aging male population this formula is also marketed toward.†

Estrogenex Depot vs. Estrogenex 2nd Generation — Choosing the Stronger Option

Estrogenex Depot tends to be stronger on estrogen blocking, using multiple aromatase inhibitors (8-Bromo, 7,8-Benzoflavone, 9-Hydroxy-Alpha-Naphthoflavone) working through several distinct pathways simultaneously, and is less focused on testosterone-boosting botanicals. Estrogenex 2nd Generation is less aggressive on estrogen blocking but makes up for it with stronger testosterone-boosting ingredients (Eurycoma Longifolia, Quercetin, Muira Puama). Choose Depot when aggressive estrogen control is the priority — such as post-cycle recovery from a wetter prohormone or during a cutting phase to reduce bloating and water retention specifically in the stomach and chest areas. Choose 2nd Generation for a more balanced, ongoing test-support approach without needing maximal aromatase suppression.†

Frequently Asked Questions

1. Can Estrogenex Depot be used both on-cycle and as PCT?
   Yes — Estrogenex Depot is versatile enough for both applications. On-cycle, it helps you stay free of unwanted estrogen-related side effects while your prohormone cycle is active. As PCT, it helps reduce the chances of estrogen-related side effects like gyno and helps get your body's hormone levels back to normal after the cycle ends.†

2. Can Estrogenex Depot help with water retention during a cut?
   Yes — this product can help reduce bloating and water retention, especially in the stomach and chest areas, making it a popular choice during cutting and dieting phases, independent of any prohormone cycle.†

3. What side effects should I watch for?
   Exceeding the recommended serving may cause serious adverse health effects, including acne, hair loss, facial hair growth (in women), aggressiveness, irritability, and — counterintuitively — increased estrogen levels if overdone. Stick to the labeled dose and discontinue immediately if you experience rapid heartbeat, dizziness, blurred vision, or similar symptoms.†

4. Is Estrogenex Depot appropriate for tested athletes?
   No. Epiandrosterone is a DHEA metabolite prohibited by WADA and NCAA. Tested athletes must not use this product.†

How to Take Hi-Tech Pharmaceuticals Estrogenex Depot

Take 1 tablet 1-3 times daily with meals. Never exceed 6 tablets per day. Use for 30 days, then take at least 30 days off before starting another cycle. Can be used on-cycle to prevent estrogen-related side effects, or as PCT to restore normal hormone levels after a prohormone cycle ends. Consult a physician or licensed healthcare professional before use, including if you have or have a family history of prostate cancer, prostate enlargement, heart disease, or low HDL ("good") cholesterol, or if you are using any other dietary supplement, prescription drug, or over-the-counter drug. Discontinue use and call a physician immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms. Not for women — may cause hair growth on the face in women. California Prop 65 Warning applies.†

Why Buy at Get Yok'd

• Real-time inventory across all five Southern California stores

• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood

• Authorized Hi-Tech Pharmaceuticals retailer — carrying Estrogenex Depot alongside Estrogenex 2nd Generation and the full Hi-Tech test support and estrogen-management lineup

• Staff who can help you choose between Estrogenex Depot and 2nd Generation based on your specific cycle and physique goals

• One of the best loyalty programs in the supplement industry — earn rewards on every purchase

Who Should Not Take Estrogenex Depot

• Not for women — may cause facial hair growth and other virilizing effects

• Consult a physician before use if you have or have a family history of prostate cancer or prostate enlargement

• Consult a physician before use if you have heart disease or low HDL ("good") cholesterol

• Not for tested athletes — contains Epiandrosterone, a DHEA metabolite prohibited by WADA and NCAA

• Do not exceed the recommended serving — excess use may cause acne, hair loss, aggressiveness, irritability, and paradoxically increased estrogen levels

• Discontinue use and call a physician immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms

• Consult a physician before use if taking any other dietary supplement, prescription drug, or over-the-counter medication

• California Prop 65 Warning applies.

• Keep out of reach of children.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.