Transparent Labs - Mushroom Stack - 90 Capsules

Transparent Labs Mushroom Stack combines three of the most clinically supported and historically significant medicinal mushrooms into one clean, organic, fully disclosed formula: 1,000mg Organic Lion's Mane, 500mg Organic CordycepsPrime Cordyceps sinensis, and 500mg Organic Reishi — 2,000mg total per 3-capsule serving. Whole fruiting body extracts. Informed Choice certified. Non-GMO, gluten-free, no artificial additives. 90 capsules, 30 servings. The three-mushroom stack covering the full adaptogenic spectrum: cognitive function, physical performance, and immune resilience in a single daily dose.†

Supplement Facts — Transparent Labs Mushroom Stack (Per 3 Capsule Serving)

• Organic Lion's Mane (Hericium erinaceus, fruit body) — 1,000mg
• Organic CordycepsPrime (Cordyceps sinensis) — 500mg
• Organic Reishi Mushroom (Ganoderma lucidum, fruit body) — 500mg
• Other Ingredients: Hypromellose (HPMC) vegetarian capsule, Vegetable Magnesium Stearate, Pure Olive Oil, Silicon Dioxide, Rice Flour
• Whole fruiting body extracts — no mycelium on grain fillers
• Organic certified. Non-GMO. Gluten-free. No artificial sweeteners, colors, or preservatives.
• Informed Choice certified. Third-party tested.
• 90 capsules per container. 30 servings.

What's Inside Transparent Labs Mushroom Stack

Why Fruiting Body vs. Mycelium on Grain Matters

Before covering the individual mushrooms, this distinction is worth understanding because it determines whether a mushroom supplement actually contains the bioactive compounds you are paying for. The mushroom supplement market is heavily populated with products made from mycelium grown on grain substrates — typically oats or rice — that are dried and ground into powder without separating the mycelium from the grain. These products can legally list high amounts of "mushroom" on the label while containing mostly grain starch and minimal actual fungal bioactives.†

Transparent Labs Mushroom Stack uses whole fruiting body extracts — the actual mushroom structure that forms above the substrate, which contains the concentrated beta-glucans, triterpenes, hericenones, erinacines, cordycepin, and other active compounds that the clinical research documents. Fruiting body extracts consistently test for higher beta-glucan concentrations (the primary immune-active compounds in medicinal mushrooms) than mycelium-on-grain products. This is not a minor quality difference — it is the difference between taking a functional mushroom supplement and taking an expensive fiber capsule.†

Organic Lion's Mane (Hericium erinaceus) — 1,000mg

Lion's Mane is the most cognitively significant ingredient in the formula and receives the highest dose at 1,000mg — double the Reishi and Cordyceps doses — reflecting its unique position as the only widely studied mushroom with documented neurotrophic effects. It is a neuroprotective and neuroregenerative mushroom with two classes of bioactive compounds exclusive to the species: hericenones (from the fruiting body) and erinacines (from the mycelium). Both classes stimulate the synthesis of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF) — proteins responsible for the growth, maintenance, and differentiation of neurons throughout the central and peripheral nervous systems.†

This NGF-stimulating mechanism is clinically meaningful and not shared by other mushroom species or most nootropic ingredients. NGF supports the formation and maintenance of cholinergic neurons — the neurons that produce acetylcholine, the primary neurotransmitter for memory, learning, and cognitive function. Research has documented that Lion's Mane administration increases neurite outgrowth (the growth of dendrites and axons that form synaptic connections) by up to 60.6% — a structural effect on brain architecture rather than a transient neurochemical effect. This is why Lion's Mane has a different quality of cognitive support than stimulant-based or cholinergic nootropics: it does not simply elevate neurotransmitter levels acutely, it supports the structural biology of the neurons that produce and respond to those neurotransmitters.†

Beyond cognition, Lion's Mane has been studied for gastrointestinal health — specifically for its ability to reduce the size and formation of gastric ulcers, maintain antioxidant levels in the GI tract's mucosal lining, and support GI epithelial integrity. The gut-brain connection makes Lion's Mane relevant to mood and cognitive performance through both neural and gastrointestinal mechanisms simultaneously. Research also suggests Lion's Mane has meaningful anti-inflammatory and antioxidant properties, contributing to the overall longevity-supporting profile of the formula.†

Organic CordycepsPrime (Cordyceps sinensis) — 500mg

Cordyceps sinensis is the energy and performance mushroom — the one with the longest documented history of use specifically for physical stamina, endurance, and vitality in Asian traditional medicine spanning over six centuries. CordycepsPrime is a concentrated fermented extract derived from Cordyceps sinensis mycelia, standardized for its active constituents including cordycepin and its derivatives, ergosterol, and rare polysaccharides.†

The primary performance mechanism of Cordyceps operates through adenosine triphosphate (ATP) synthesis. Cordyceps sinensis contains cordycepin (3'-deoxyadenosine), a structural analog of adenosine that supports cellular ATP production through purinergic signaling pathways. By supporting the body's ability to synthesize and utilize ATP — the universal energy currency of every cell — Cordyceps improves the efficiency of energy delivery to working muscle tissue. The practical result in research is improved VO2 max, improved time to exhaustion, and reduced perceived exertion during moderate-to-high intensity exercise.†

Beyond the physical performance angle, Cordyceps has documented anti-aging properties, with research suggesting it can improve memory, libido, and immune function. Its polysaccharide content provides the immune-supporting beta-glucan activity that all three mushrooms in this formula contribute, while its unique cordycepin content differentiates it from the other two through its ATP-related energy mechanism. Cordyceps has also been studied for its effects on oxygen utilization — research documents improvements in how efficiently the body uses available oxygen during exercise, which is relevant for both cardiovascular and muscular endurance.†

Organic Reishi Mushroom (Ganoderma lucidum) — 500mg

Reishi is the immune and longevity mushroom — Ganoderma lucidum, known as Lingzhi in Traditional Chinese Medicine, where it has been called the "mushroom of immortality" for over 2,000 years. Reishi contains two primary classes of bioactive compounds: beta-glucan polysaccharides that directly modulate immune function, and triterpene compounds called ganodermic acids with potent anti-inflammatory, antioxidant, and hepatoprotective properties.†

The immune-supporting mechanism of Reishi is direct and well-documented. Beta-glucans in Reishi bind to pattern recognition receptors on macrophages, natural killer cells, and dendritic cells, activating innate immune responses and upregulating the production of cytokines that coordinate both innate and adaptive immunity. The immunostimulating effect of Reishi polysaccharides has been validated in human clinical research — a meta-analysis of 373 subjects found that individuals with early-stage cancerous tumors had a 27% higher likelihood of responding to chemotherapy or radiotherapy when supplementing with Reishi extract, an effect attributed to the enhanced immune surveillance that Reishi polysaccharides support.†

The ganodermic acids in Reishi provide the anti-inflammatory and liver-protective dimension. These triterpenes inhibit histamine release in mast cells, reducing pro-inflammatory markers in susceptible tissues and contributing to what the Transparent Labs formula describes as "fortifying the body's antioxidant capacity and immune defenses." Ganodermic acids also demonstrate hepatoprotective properties, supporting liver function through their antioxidant activity on liver tissue — a benefit that complements the detoxification and immune functions of the liver that are relevant to athletes and anyone under regular metabolic stress.†

Reishi's calming and sleep-supporting properties are equally valued in traditional use and increasingly supported by modern research. Reishi contains compounds that influence GABA receptor activity and promote parasympathetic nervous system dominance, contributing to the stress-adaptive effects that make all three mushrooms in this formula true adaptogens — substances that help the body maintain physiological equilibrium under physical, mental, or immune stress.†

Frequently Asked Questions About Transparent Labs Mushroom Stack

1. Why do medicinal mushrooms need to be taken daily for weeks to work?
   Medicinal mushrooms operate through fundamentally different mechanisms than stimulants or acute supplements. Their active compounds — beta-glucans, triterpenes, erinacines, hericenones, and cordycepin — work by modulating gene expression, supporting immune cell development, stimulating neurotrophic factor production, and training the immune system to respond more effectively over time. These are cumulative, adaptive processes rather than acute pharmacological effects. Lion's Mane's NGF-stimulating effects require consistent daily exposure for neuronal growth to accumulate into measurable cognitive improvements. Reishi's immune-modulating effects build as the immune system repeatedly encounters and responds to beta-glucan signaling. Most research on these mushrooms uses 4-12 week supplementation periods for this reason. Transparent Labs recommends consistent daily use for at least 3-4 weeks before evaluating full effects, though some users report initial cognitive and energy benefits within the first few days.†
2. How does Mushroom Stack compare to mushroom coffee or mushroom gummies?
   Mushroom coffees, teas, and gummies typically use much lower doses than what appears in dedicated capsule supplements — they are delivery vehicles primarily for the coffee or candy format, with mushroom extracts added at low doses as functional marketing rather than therapeutic dosing. A typical mushroom coffee contains 250-500mg total mushroom per serving across multiple species, meaning each species might receive 50-100mg — compared to the 1,000mg Lion's Mane and 500mg each Cordyceps and Reishi in Transparent Labs Mushroom Stack. Additionally, many mushroom coffees and gummies use mycelium-on-grain rather than fruiting body extracts. For genuine functional mushroom supplementation at researched doses, dedicated capsule supplements using fruiting body extracts are categorically more effective than functional food formats.†
3. Can I take Mushroom Stack with my other Transparent Labs supplements?
   Yes — Mushroom Stack contains no stimulants, hormones, or compounds with significant interaction concerns with standard supplements. It stacks cleanly with all Transparent Labs pre-workouts, protein, creatine, KSM-66 Ashwagandha, Omega-3, and Vitamin D3K2. KSM-66 plus Mushroom Stack is a particularly strong wellness foundation stack — both are adaptogens, but Ashwagandha targets cortisol and HPA axis regulation while mushrooms target immune function, cognitive neurotrophic support, and cellular energy. Together they cover the stress-immunity-cognition axis more comprehensively than either alone.†
4. Who benefits most from Mushroom Stack?
   Four groups in particular. Athletes who want performance and recovery support without stimulants — Cordyceps addresses ATP efficiency and VO2 max while Lion's Mane supports the cognitive focus that training demands. Individuals prioritizing cognitive function, memory, and long-term brain health — Lion's Mane at 1,000mg daily is genuinely one of the most meaningful things you can take for neuroprotection and cognitive support over the long term. Individuals who get sick frequently or whose immunity is under stress from heavy training, sleep deprivation, or life demands — Reishi's beta-glucan and triterpene immune support addresses this directly. And anyone taking a longevity-oriented approach to health supplementation — all three mushrooms have documented anti-aging, antioxidant, and cellular protection properties that contribute to the same healthy aging goals as omega-3s and vitamin D.†

How to Take Transparent Labs Mushroom Stack

Take 3 capsules daily, preferably with a meal or as directed by your healthcare professional. Can be taken with or without food — some users prefer morning use to leverage Lion's Mane's cognitive support throughout the day, while others prefer evening use for Reishi's relaxation and immune support. Consistent daily use for at least 3-4 weeks is required to meaningfully assess the cognitive, immune, and energy effects. Works best as a consistent daily habit rather than an occasional or as-needed supplement.†

Other Transparent Labs Wellness Products at Get Yok'd

• Transparent Labs KSM-66 Ashwagandha — adaptogenic stress and cortisol management; pairs with Mushroom Stack for complete adaptogen coverage
• Transparent Labs Omega-3 — foundational wellness stack; DHA independently supports brain health alongside Lion's Mane NGF effects
• Transparent Labs Vitamin D3 K2 — immune and bone health complement to Reishi's immune support
• Transparent Labs ZMO — zinc, magnesium, and oyster for recovery and vitality to complete the wellness foundation

Why Buy Supplements at Get Yok'd

• Real-time inventory across all five Southern California stores
• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
• Authorized retailer of Transparent Labs
• One of the best loyalty programs in the supplement industry — earn rewards on every purchase
• Owned and operated by fitness enthusiasts who actually use what we sell

Who Should Not Take Transparent Labs Mushroom Stack

• Individuals with known mushroom or fungal allergies — discontinue use if you experience allergic reaction symptoms
• Consult a physician before use if pregnant or nursing
• Consult a physician before use if taking immunosuppressant medications — Reishi and Lion's Mane both have immune-modulating properties that may interact with immunosuppressants
• Consult a physician before use if taking blood-thinning medications — Reishi has mild anticoagulant properties
• Consult a physician before use if you have a scheduled surgery — discontinue use 2 weeks prior
• Consult a physician before use if you have a bleeding disorder
• Consult a physician before use if taking any prescription medications
• Keep out of reach of children

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.