Global Formulas - bioBOOST

Global Formulas bioBOOST is a high-potency natural testosterone support formula built around ultra-concentrated standardized botanical extracts and hormone-modulating compounds — designed for both men and women, with zero synthetic hormones and no prohormone compounds. The anchor of the formula is 750mg of Tribulus Terrestris standardized to 20% Protodioscin, one of the highest standardization ratios commercially available, alongside 150mg of DIM (Diindolylmethane) for estrogen regulation and 20-Hydroxyecdysterone for protein synthesis and muscle density. Available in 120 capsule (15-serving) and 240 capsule (30-serving) sizes. Men: 4 capsules twice daily. Women: 2-3 capsules twice daily. Cycle 10 weeks on, 2 weeks off. Do not exceed 8 capsules in 24 hours. Stacks with bioFORCE and bioSLEEP for the complete Global Formulas muscle growth stack. Suitable for use as a PCT supplement following prohormone cycles.†

Supplement Facts — Global Formulas bioBOOST (Per Full Serving)

Confirmed Key Ingredients

• Tribulus Terrestris (20% Protodioscin) — 750mg
• DIM (Diindolylmethane) — 150mg
• 20-Hydroxyecdysterone — muscle density and protein synthesis
• Additional ultra-concentrated botanical extracts for libido, recovery, and well-being support

• Available in 120 capsules (15 full servings) and 240 capsules (30 full servings)
• Men: 4 capsules twice daily (AM upon rising + PM before exercise or bedtime)
• Women: 2-3 capsules twice daily
• For libido/sexual performance: 4 capsules 30-60 minutes before activity
• Do not exceed 8 capsules in any 24-hour period
• Cycle: 10 weeks on, 2 weeks off
• Safe for women — no synthetic hormones
• Suitable as PCT after prohormone cycles

The Core Approach — Natural Hormonal Optimization, Not Replacement

bioBOOST operates on the principle that supporting the body's own endogenous testosterone production pathway produces more sustainable and side-effect-free results than introducing exogenous androgens. Rather than converting to testosterone directly (as prohormone products do), bioBOOST works through three complementary mechanisms: stimulating the upstream hormonal signal (LH amplification via Tribulus/Protodioscin), regulating the estrogen balance that determines how much free testosterone is available (DIM), and directly supporting protein synthesis and muscle quality through a non-hormonal anabolic mechanism (20-Hydroxyecdysterone). These three mechanisms operate at different points in the hormonal and anabolic cascade — addressing production, regulation, and utilization simultaneously.†

The Three Primary Active Compounds

Tribulus Terrestris (20% Protodioscin) — 750mg — The Luteinizing Hormone Amplifier

Tribulus Terrestris is an herb whose steroidal saponins — particularly Protodioscin — have documented effects on luteinizing hormone (LH) secretion. LH is the pituitary hormone that travels to the Leydig cells in the testes (in men) and signals them to produce testosterone. The more LH present and active, the stronger the signal to the testes to produce testosterone. In women, LH plays an analogous role in ovarian function and contributes to hormonal balance and well-being.†

The standardization percentage is the decisive variable in Tribulus supplementation. Most mass-market Tribulus supplements are standardized to 45% saponins total — which sounds high until you understand that Protodioscin is a specific saponin fraction within that total, and a 45% total saponin extract may contain very little actual Protodioscin. Global Formulas bioBOOST specifies 20% Protodioscin standardization directly — meaning 20% of the 750mg extract (150mg) is confirmed Protodioscin. This is the specific compound with documented LH-stimulating effects in the research literature on Tribulus. At 150mg of actual Protodioscin from 750mg of 20%-standardized extract, bioBOOST is delivering a Protodioscin dose meaningfully above what most undifferentiated Tribulus products provide, even at similar total Tribulus weights.†

DIM (Diindolylmethane) — 150mg — The Estrogen Regulator

DIM (Diindolylmethane) is a compound produced in the body from the digestion of indole-3-carbinol (I3C), found naturally in cruciferous vegetables — broccoli, kale, Brussels sprouts, cauliflower. DIM's mechanism in hormonal support is estrogen metabolism modulation: it promotes the conversion of estrogen toward the 2-hydroxy (2-OHE) pathway rather than the 16-hydroxy (16-OHE) pathway. The 2-hydroxy estrogen metabolites are considered "good" estrogens — weaker-acting, with some anti-estrogenic properties. The 16-hydroxy metabolites are more potent and have been associated with tissue stimulation effects. By shifting estrogen metabolism toward the 2-OHE pathway, DIM reduces the effective estrogenic activity in the body without blocking estrogen production entirely.†

In the context of testosterone support, DIM's role is about the testosterone-to-estrogen ratio rather than testosterone production itself. Men and women with elevated estrogenic activity relative to their testosterone levels experience the downstream effects of estrogen dominance — reduced free testosterone, softer physique, water retention, mood changes, reduced libido. DIM addresses this by regulating estrogen metabolism without the harsh, complete estrogen suppression of pharmaceutical aromatase inhibitors or SERM compounds. At 150mg, bioBOOST is delivering a meaningful daily DIM dose — research on DIM typically uses 100-300mg daily for hormonal effects, placing 150mg solidly in the therapeutic range.†

The DIM component is also the primary reason bioBOOST is positioned as a PCT (post-cycle therapy) supplement for users coming off prohormone cycles. When a prohormone cycle ends and exogenous androgen input stops, the body's natural testosterone production recovers while estrogen levels may remain temporarily elevated (post-cycle estrogen rebound). DIM's estrogen metabolism modulation supports the transition back to baseline hormonal balance, helping preserve the muscle quality and body composition gains from the cycle.†

20-Hydroxyecdysterone — The Non-Hormonal Anabolic Layer

20-Hydroxyecdysterone (20-HE, also called Ecdysterone) is a plant-derived ecdysteroid — a class of steroid hormones from plants and insects that produce anabolic effects in mammalian muscle tissue through mechanisms that operate through estrogen receptor beta (ERβ) activation rather than androgen receptor binding. This is the key distinction that makes 20-HE relevant in a testosterone booster context: it adds anabolic protein synthesis stimulus that is entirely independent of androgen receptor activity, meaning it works whether testosterone levels are high or low, and contributes to muscle quality and density without any androgenic side effects or hormonal implications.†

Research on 20-Hydroxyecdysterone has documented protein synthesis increases and improvements in body composition in human trials, most notably a 2019 clinical study published in Archives of Toxicology which found that ecdysterone supplementation produced significantly greater increases in muscle mass and strength compared to placebo in resistance-trained men. The study also found that ecdysterone's muscle-building mechanism operates through ERβ in a manner that does not produce the side effects (hormonal suppression, liver stress, cardiovascular effects) associated with anabolic steroids. WADA added ecdysterone to its monitoring list in 2021 specifically because the anabolic effects are documented and meaningful — though it has not been added to the prohibited list as of the current date. Athletes in tested sports should verify current WADA status before using bioBOOST.†

Why bioBOOST Is Safe for Women — and Why Half the User Base Is Female

Global Formulas reports that approximately half of bioBOOST users are women — and the formula genuinely supports this use case. Unlike prohormones (which contain DHEA-derived androgenic compounds that cause virilization in women) or aggressive testosterone boosters that use high-dose DHEA or other androgenic precursors, bioBOOST's active ingredients work through hormonal pathways that are relevant to both sexes.†

Women produce testosterone naturally in the adrenal glands and ovaries — typically 1/10 to 1/15 of male levels — and testosterone in women plays meaningful roles in libido, muscle maintenance, energy, mood, and cognitive function. Low testosterone in women is a documented clinical syndrome with similar symptom profiles to low testosterone in men. bioBOOST's LH-stimulating Tribulus/Protodioscin supports natural sex hormone production in women's gonads through the same LH mechanism. DIM's estrogen metabolism modulation is particularly relevant for women who experience estrogen dominance — a common hormonal imbalance in women that affects body composition, mood, and menstrual regularity. 20-Hydroxyecdysterone's ERβ-mediated protein synthesis has no sex-specific limitations. The female dosing recommendation (2-3 caps twice daily versus men's 4 caps) reflects appropriate dose adjustment for body weight and hormonal baseline differences.†

bioBOOST as PCT — Post-Prohormone Cycle Support

Global Formulas explicitly positions bioBOOST as suitable PCT support for users coming off prohormone cycles. Prohormone cycles suppress the HPG (hypothalamic-pituitary-gonadal) axis through androgenic feedback — the exogenous androgens from prohormone conversion signal the hypothalamus and pituitary to reduce LH and FSH secretion, which reduces natural testosterone production during the cycle. When the cycle ends, HPG axis recovery takes time — typically 4-8 weeks depending on cycle length, compounds used, and individual physiology.†

During this recovery window, natural testosterone production is below baseline and estrogen may be relatively elevated — the classic post-cycle state that produces soft physique, mood decline, libido reduction, and accelerated catabolism. bioBOOST addresses this through its LH-stimulating Tribulus component (which accelerates HPG axis recovery by driving LH secretion back toward normal) and DIM's estrogen regulation (which manages the post-cycle estrogen rebound). Users who run bioBOOST as a standalone PCT or who stack it with Hi-Tech Arimiplex are using the natural hormone support layer of a PCT alongside the aromatase inhibitor/SERM layer — covering both estrogen management and natural testosterone restoration simultaneously.†

Note: bioBOOST is not a pharmaceutical PCT and should not replace Arimiplex or other aromatase inhibitors/SERMs for heavy prohormone cycles. For moderate prohormone cycles or as a complement to a pharmaceutical PCT, bioBOOST adds natural hormone support that pharmaceutical PCT compounds alone don't address.†

bioBOOST in the Global Formulas Stack

Global Formulas recommends stacking bioBOOST with bioFORCE (their intra-workout mass and strength formula) and bioSLEEP GH (their sleep and growth hormone support formula) for the ultimate muscle growth stack. The three products address the anabolic environment at different times of day: bioBOOST drives natural testosterone and hormone optimization throughout the day (AM and PM dosing), bioFORCE maximizes training performance and intra-workout anabolism, and bioSLEEP GH supports growth hormone release and muscle repair during sleep — the period when the majority of muscle protein synthesis and recovery occurs. Stack with bioPUMP'D or Super bioFREAK WTF for pre-workout performance.†

Frequently Asked Questions

1. How quickly does bioBOOST produce results?
   Global Formulas states users typically notice positive effects within the first 7-10 days of consistent use. The libido and well-being effects from the botanical extracts tend to be noticed earliest. Lean mass and muscle density improvements from the 20-Hydroxyecdysterone are typically noticeable at 3-4 weeks of consistent use. Maximum hormonal optimization results from the Tribulus/Protodioscin component develop over 4-8 weeks as the compound's effects on LH and testosterone production accumulate.†
2. Why does bioBOOST need to be cycled (10 weeks on, 2 weeks off)?
   Tribulus Terrestris at high standardizations can produce LH desensitization with continuous use over extended periods — the pituitary can become less responsive to repeated LH-stimulating signals if they are constant and uninterrupted. A 2-week break after 10 weeks of use resets the pituitary's responsiveness, maintaining the formula's effectiveness over repeated cycles. The cycling protocol also applies to 20-Hydroxyecdysterone, which benefits from a periodic washout to preserve receptor sensitivity.†
3. Can bioBOOST be used as a standalone PCT or does it need to be stacked with Arimiplex?
   For milder prohormone cycles (1-ANDRO single-compound, Winstrol, shorter cycles), bioBOOST as a standalone PCT provides meaningful natural testosterone and estrogen support. For heavier cycles involving multiple compounds, wet prohormones (4-ANDRO, Sustanon 250), or longer cycle lengths, stacking bioBOOST with Arimiplex (aromatase inhibitor + SERM) provides more comprehensive PCT coverage. bioBOOST handles the natural LH amplification and estrogen metabolism modulation; Arimiplex handles the aromatase inhibition and SERM receptor competition. The two products are complementary in a full PCT stack.†
4. Is bioBOOST appropriate for tested athletes?
   The Tribulus and DIM components are not prohibited by WADA or NCAA. However, 20-Hydroxyecdysterone is currently on WADA's Monitoring Program — it is not prohibited but is being monitored for potential future prohibition based on its documented anabolic effects. Athletes in tested sports should verify the current status of ecdysterone with their governing body before using bioBOOST.†

How to Take Global Formulas bioBOOST

Men: Take 4 capsules twice daily — upon rising in the AM and before PM exercise or bedtime. Women: Take 2-3 capsules twice daily at the same times. For libido and sexual performance: take 4 capsules 30-60 minutes before activity. Do not exceed 8 capsules in any 24-hour period. Cycle 10 weeks on, 2 weeks off. Stack with bioFORCE and bioSLEEP GH for maximum muscle growth results. Can be used during or after prohormone cycles as natural hormonal support. Consult a physician before use if taking any hormone medications, prescription drugs, or having any hormonal condition. Not for pregnant or nursing women.†

Why Buy at Get Yok'd

• Real-time inventory across all five Southern California stores
• Available in Burbank, Glendale, Glendale Galleria, Pasadena, and North Hollywood
• Authorized retailer of Global Formulas — carrying the full lineup including bioFORCE, bioSLEEP GH, and the complete muscle growth stack
• Staff who can walk you through PCT planning and natural test support protocols in person at any location
• One of the best loyalty programs in the supplement industry — earn rewards on every purchase

Who Should Exercise Caution with bioBOOST

• Not for pregnant or nursing women
• Individuals with hormone-sensitive conditions (estrogen-receptor positive cancers, PCOS, endometriosis) should consult a physician before use — DIM affects estrogen metabolism
• Individuals with thyroid conditions should consult a physician — DIM at high doses can affect thyroid hormone metabolism
• Individuals taking hormonal medications (HRT, birth control, testosterone replacement) should consult a physician before adding bioBOOST
• Athletes in tested sports should verify WADA status of 20-Hydroxyecdysterone before use — it is on the monitoring program
• Consult a physician before use if taking any prescription medications
• Keep out of reach of children.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.